444221

MMP-1/MMP-9 Substrate, Fluorogenic

An excellent quenched fluorescence substrate for MMP-1 and MMP-9.

• 別名: MMP-1/MMP-9 Substrate, Fluorogenic
• 実験式（ヒル表記法）: C₄₉H₆₈N₁₄O₁₂S
• 分子量: 1077.22
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: yellow
• 溶解性: 50% acetic acid: 10 mg/mL
• 蛍光検出: λ_ex ~365 nm; λ_em ~450 nm
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

An excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining K_i values. Excitation max: ~365 nm; emission max: ~450 nm.

An excellent quenched fluorescence substrate for MMP-1 and MMP-9. Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining K_i values.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
MMP-1, MMP-9

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

シーケンス

{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]

その他情報

Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable