405210

ID-8

A cell-permeable indole compound that, when added to murine D3ES ESC (embryonic stem cell) cultures in the absence of serum and MEF (murine embryonic fibroblast) feeder cells, serves as a cheaper, chemical alternative to LIF

• 別名: ID-8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-indol-6-ol
• 実験式（ヒル表記法）: C₁₆H₁₄N₂O₄
• CAS番号: 147591-46-6
• 分子量: 298.29
• UNSPSCコード: 12352200
• NACRES: NA.51

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: powder
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: yellow
• 溶解性: DMSO: 50 mg/mL
• 輸送温度: ambient
• 保管温度: 2-8°C

詳細

詳細

A cell-permeable indole compound that, when added (10 µM) to murine D3ES ESC (embryonic stem cell) cultures in the absence of serum and MEF (murine embryonic fibroblast) feeder cells, serves as a cheaper, chemical alternative to LIF (1,000 units/ml) for expanding ESCs in their undifferentiated state. Long-term murine ESCs maintained under ID-8 are capable of differentiating and EBs (Embryoid Bodies) formation upon ID-8 removal. Also claimed to maintain human ESCs in their pluripotent state in the absence of MEF.

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

その他情報

Miyabayashi, T., et al. 2008. Biosci. Biotechnol. Biochem.72, 1242.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3