239900

Cypermethrin

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

• 別名: Cypermethrin
• 実験式（ヒル表記法）: C₂₂H₁₉Cl₂NO₃
• CAS番号: 52315-07-8
• 分子量: 416.30
• MDL番号: MFCD00055328
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 詳細: Merck USA index - 14, 2767
• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: oil
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 溶解性: DMSO: 15 mg/mL; ethanol: 5 mg/mL
• 輸送温度: ambient
• 保管温度: 2-8°C
• SMILES記法: ClC(=CC1C(C1C(=O)OC(c2cc(ccc2)Oc3ccccc3)C#N)(C)C)Cl
• InChI: 1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
• InChI Key: KAATUXNTWXVJKI-UHFFFAOYSA-N

詳細

詳細

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC₅₀ = 40 pM). May also have varied effects on ion channels.

生物化学的／生理学的作用

Primary Target
calcineurin

Product does not compete with ATP.

Target IC₅₀: 40 pM against calcineurin (protein phosphatase 2B

警告

Toxicity: Toxic (F)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08,GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302 + H332,H315,H317,H335,H373,H410
• 注意書き: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P314
• 危険有害性の分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
• ターゲットの組織: Nervous system, Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): 212.0 °F - closed cup
• 引火点(℃): 100 °C - closed cup