219385

Cathepsin B Inhibitor II

The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 別名: Cathepsin B Inhibitor II, Ac-LVK-CHO
• 実験式（ヒル表記法）: C₁₉H₃₆N₄O₄
• 分子量: 384.51
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: water: 1 mg/mL
• 輸送温度: ambient
• 保管温度: −70°C

詳細

詳細

A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) compared to leupeptin (IC₅₀ = 310 nM).

Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) than of leupeptin (IC₅₀ = 310 nM). Note: this peptide forms cyclic isomers.

Note: this peptide forms cyclic isomers.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
cathepsin B

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 4 nM against cathepsin B

警告

Toxicity: Standard Handling (A)

シーケンス

Ac-Leu-Val-lysinal

再構成

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

その他情報

McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable