218753

Caspase-5 Inhibitor I

Single spot by TLC, solid, Caspase-5 inhibitor, Calbiochem^®

• 別名: Caspase-5 Inhibitor I, Z-WE(OMe)HD(OMe)-FMK
• 実験式（ヒル表記法）: C₃₇H₄₂FN₇O₁₀
• 分子量: 763.77
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• product name: Caspase-5 Inhibitor I, Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.
• 品質水準: 100
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated
• 色: white
• 溶解性: DMSO: 5 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICE_rel-III, TY), as well as caspase-1 and caspase-4.

A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
caspase-1, caspase-4, caspase-5, caspase-8

Reversible: no

警告

Toxicity: Standard Handling (A)

シーケンス

Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*

物理的形状

Supplied as a trifluoroacetate salt.

再構成

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.

アナリシスノート

single spot by TLC

その他情報

Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable