16-455

Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate

clone 4A4, Upstate^®, from mouse

• 別名: 4A4, anti-phosphoserine, phosphoserine antibody, pan-phosphoserine
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: peroxidase conjugate
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 4A4, monoclonal
• 化学種の反応性（ホモロジーによる予測）: all
• メーカー／製品名: Upstate^®
• テクニック: western blot: suitable
• アイソタイプ: IgG1
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer)

詳細

詳細

The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.

特異性

Recognizes proteins containing phosphoserine residues, regardless of origin.

免疫原

Epitope: phosphoserine

Phosphoserine conjugated to KLH.

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
一般的な翻訳後修飾

Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate is an antibody against Phosphoserine for use in WB.

品質

Routinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.

ターゲットの説明

Varies

物理的形状

Protein G Purified

100 μL of protein G purified mouse IgG1 in PBS containing 0.05% Kathon^® and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.

保管および安定性

6 months at 2-8°C from date of shipment.
NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

法的情報

Kathon is a registered trademark of Rohm and Haas Co.

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids