おすすめの製品
由来生物
mouse
品質水準
結合体
FITC conjugate
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
monoclonal
化学種の反応性（ホモロジーによる予測）
all
メーカー／製品名
Upstate®
テクニック
immunocytochemistry: suitable
輸送温度
wet ice
ターゲットの翻訳後修飾
phosphorylation (pSer/pThr)
詳細
This antibody recognizes a variety of proteins that are phosphorylated during mitosis.
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
アプリケーション
Research Category
エピジェネティクス及び核内機能分子
エピジェネティクス及び核内機能分子
Research Sub Category
細胞周期、DNA複製及び修復
細胞周期、DNA複製及び修復
Detect phospho-Ser/Thr-Pro also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, FITC conjugate (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC.
For applications in which an FITC conjugate is advantageous, such as ICC.
品質
routinely evaluated in immunocytochemistry on A431 mitotic cells fixed with 3.7% paraformaldehyde
物理的形状
TBS, pH 8.0, 0.05% sodium azide and 30% glycerol
保管および安定性
Stable for 1 year at -20°C from date of shipment. Store in the dark. For maximum recovery of product, centrifuge the vial.
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 2
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Timothy R Rudd,Katarzyna A Uniewicz,Alessandro Ori,Scott E Guimond,Mark A Skidmore et al.
Organic & Biomolecular Chemistry null
William Clay Gustafson et al.
Cancer cell, 26(3), 414-427 (2014-09-02)
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Kuang, J, et al.
Molecular Biology of the Cell, 5, 135-145 (1994)
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Shan, W; Akinfenwa, PY; Savannah, KB; Kolomeyevskaya, N; Laucirica, R; Thomas, DG; Odunsi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null
The mitosis-specific monoclonal antibody MPM-2 recognizes phosphoproteins associated with the nuclear envelope in Chlamydomonas reinhardtii cells.
Harper, J D, et al.
European Journal of Cell Biology, 51, 272-278 (1990)
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