14-919-M

LRRK2 Protein, active, 10 µg

Active, N-terminal FLAG-tagged, recombinant, human LRRK2, amino acids 970-end. For use in Kinase Assays.

• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

特性

• 由来生物: human
• 品質水準: 100; 300
• リコンビナント: expressed in baculovirus infected Sf21 cells
• 分子量: M_w 180 kDa
• メーカー／製品名: Upstate^®
• テクニック: activity assay: suitable (kinase)
• GenBankアクセッション番号: BC117180
• UniProtアクセッション番号: Q5S007
• 遺伝子情報: human ... LRRK2(120892)

詳細

詳細

Product Source: N-terminal FLAG-tagged, recombinant, human LRRK2 amino acids 970-end, expressed by baculovirus in Sf21 insect cells.

This protein is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

包装

Also available in 250μg size as catalog # 14-919M and in bulk as catalog # 14-919-K.

品質

Routinely evaluated by phosphorylation of ERMtide (RLGRDKYKTLRQIRQ)

物理的形状

50mM Tris/HCl pH7.4, 300mM NaCl, 20mM β-glycerophosphate, 0.25mM sodium orthovanadate, 10mM NaF, 150µg/ml FLAG peptide, 20% v/v glycerol, 1mM benzamidine, 0.2mM PMSF, 5mM DTT. Frozen solution.

その他情報

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法的情報

GenBank is a registered trademark of United States Department of Health and Human Services

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3