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ligand
(Trimethylammoniumethyl)
品質水準
物質
polypropylene housing
製品種目
Eshmuno®
形状
prepacked column
パラメーター
≤8 bar pressure
1000 cm/hr max. flow rate
ベッド長
100 mm
ベッド容積
5 mL
カラム内径
8 mm
容量
5 mL
マトリックス活性基
Polyvinyl Ether
平均粒径
85 μm
キャパシティ
~150 mg, BSA binding capacity
アプリケーション
mAb
recombinant protein
vaccine development
分離法
anion exchange
保管温度
15-25°C
関連するカテゴリー
詳細
8 x 100mm
MiniChrom Pre-packed Columns with Eshmuno® cation exchange resin is designed for the rapid evaluation of resins for bioprocess development. The results obtained for biomolecule separations are generally comparable to the results achieved using laboratory-scale columns (e.g. 100 x 16 mm ID).
In bioprocess design, the MiniChrom columns can be used to rapidly determine whether a target biomolecule is bound to and can be eluted from the Eshmuno® resin, as well as determine whether an appropriate target yield may be achieved and whether major contaminants could potentially be removed.
MiniChrom columns are designed for process development, method optimization and parameter screening as well as sample preparation. MiniChrom columns are quality checked for HETP and asymmetry, providing superior reproducibility, excellent scalability, convenient comparison of different chromatography media.
MiniChrom columns are made from biocompatible polypropylene (PP) and polyethylene (PE) and are available in 1 and 5 mL bed volumes. The 8mm diameter columns allow for scale-up from 1 to 5mL column volumes, with a constant internal diameter. These columns are compatible with any chromatographic work station, HPLC system or peristaltic pump.
In bioprocess design, the MiniChrom columns can be used to rapidly determine whether a target biomolecule is bound to and can be eluted from the Eshmuno® resin, as well as determine whether an appropriate target yield may be achieved and whether major contaminants could potentially be removed.
MiniChrom columns are designed for process development, method optimization and parameter screening as well as sample preparation. MiniChrom columns are quality checked for HETP and asymmetry, providing superior reproducibility, excellent scalability, convenient comparison of different chromatography media.
MiniChrom columns are made from biocompatible polypropylene (PP) and polyethylene (PE) and are available in 1 and 5 mL bed volumes. The 8mm diameter columns allow for scale-up from 1 to 5mL column volumes, with a constant internal diameter. These columns are compatible with any chromatographic work station, HPLC system or peristaltic pump.
特徴および利点
Eshmuno® Q chromatography resin enables:
Superior productivity for downstream processing of biomolecules
- Purification of acidic and neutral proteins and peptides from different sources, including plasma
Superior productivity for downstream processing of biomolecules
- High flow rate versus pressure-flow behavior
- Excellent removal of impurities, such as HCP, leached Protein A, and viruses
- Robust and safe packing procedures
- Strong chemical stability
法的情報
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
試験成績書（COA）
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