1.00399

N,N-Dimethylacetamide

for headspace gas chromatography SupraSolv^®

• 別名: N,N-Dimethylacetamide, Acetic acid dimethylamide, Acetyldimethylamine, DMAC, DMA, DMA
• 化学式: CH₃CON(CH₃)₂
• CAS番号: 127-19-5
• 分子量: 87.12
• MDL番号: MFCD00008686
• UNSPSCコード: 12352111
• EC Index Number: 204-826-4
• NACRES: NA.03

特性

• 蒸気圧: 1.76 hPa ( 20 °C)
• 品質水準: 100
• 製品種目: SupraSolv^®
• アッセイ: ≥99.8% (GC)
• 形状: liquid
• 自己発火温度: 400 °C
• 有効性: 5830 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 1.7-11.5 % (v/v)
• テクニック: GC-HS: suitable
• pH: 4 (20 °C, 200 g/L in H₂O)
• bp: 165-166 °C/1013 hPa
• mp: -20 °C
• 転移温度: flash point 64 °C
• 溶解性: soluble >1000 g/L
• 密度: 0.94 g/cm³ at 20 °C
• 保管温度: 2-30°C
• InChI: 1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
• InChI Key: FXHOOIRPVKKKFG-UHFFFAOYSA-N

詳細

詳細

SupraSolv^® high-purity solvents for headspace gas chromatography (HS-GC) are developed particularly for the analysis of residual solvents (RS) in drug substances, excipients and drug products according to ICH (International Council for Harmonizaton of Technical Requirements for Registration of Pharmaceuticals for Human Use) Guideline Q3C»Impurities: Guideline for Residual Solvents«, European Pharmacopeia (Ph. Eur. Chapter 2.4.24) and United States Pharmacopeia (USP Chapter 467).

アプリケーション

Suitable as a solvent for analysis of residual solvents of ICH classes 1, 2 and 3 according to Ph. Eur. and USP:

• Every residual solvent of class 1 acc. ICH ≤ 1 µg/g
• Every residual solvent of class 2 acc. ICH ≤ 10 µg/g
• Every residual solvent of class 3 acc. ICH ≤ 50 µg/g

特徴および利点

• high application reliability due to the application test performed on every batch produced
• application-oriented quality due to specified concentrations of residual solvents as defined by ICH

その他情報

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

法的情報

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07,GHS08
• シグナルワード: Danger
• 危険有害性情報: H312 + H332 - H319 - H360D
• 注意書き: P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
• 保管分類コード: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• 引火点(°F): 147.2 °F - closed cup
• 引火点(℃): 64 °C - closed cup