1.00164

ホウ酸

cryst., EMPROVE^® API, Ph. Eur., BP, NF

• 別名: Orthoboric acid, Trihydroxidoboron
• 化学式: H₃BO₃
• CAS番号: 10043-35-3
• 分子量: 61.83
• MDL番号: MFCD00011337
• UNSPSCコード: 12352106
• EC Index Number: 233-139-2

特性

• 認証: BP; NF; Ph. Eur.
• 品質水準: 600
• 蒸気圧: 2.6 mmHg ( 20 °C)
• 製品種目: EMPROVE^® API
• アッセイ: 99.5-100.5% (alkalimetric)
• 形状: solid
• 有効性: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• mp: 160 °C (dec.) (lit.)
• 溶解性: 49.2 g/L
• 密度: 1.489 g/cm³ at 23 °C
• かさ密度: 400‑600 kg/m³
• 微量陰イオン: sulfate (SO₄^2-): ≤0.04%
• 微量陽イオン: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• アプリケーション: liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• 保管温度: 2-25°C
• SMILES記法: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI Key: KGBXLFKZBHKPEV-UHFFFAOYSA-N

詳細

詳細

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H360FD
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Repr. 1B
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable