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抗体製品の状態
purified antibody
品質水準
アッセイ
>50% (SDS-PAGE)
テクニック
activity assay: suitable
western blot: suitable
詳細
Histone H2B is one of four core histones that form an octameric structure required for the packaging of DNA into nucleosomes, the most basic level of chromatin arrangement. Histones undergo a number of post-translational modifications (PTM) at their N- and C-terminal tails which can influence chromatin structure and stability and consequently, transcription, and DNA replication and repair. The most widely studied of these modifications are methylation, phosphorylation, and acetylation which may produce different effects on gene regulation depending on the number and pattern of modifications. Histone H2B undergoes acetylation at lysines 5, 15, and 20. It is also phosphorylated in apoptotic cells during DNA fragmentation, possibly in a caspase-dependent manner.
Human recombinant H2B expressed in E. Coli
アプリケーション
Chromatin assembly, Western blot (control), Kinase Assay
物性
~17 kDa
物理的形状
Liquid in Dulbecco′s PBS. Frozen solution.
保管および安定性
Stable for 12 months at -80°C from date of receipt. Avoid multiple freeze/thaw cycles.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
試験成績書(COA)
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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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