880124X

DSPE-PEG(2000) Folate

Avanti Research^™ - A Croda Brand 880124X

• 別名: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000] (ammonium salt):methanol (9:1)
• CAS番号: 1236288-25-7
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 形状: liquid
• 包装: pkg of 1 × 1 mL (880124X-10mg); pkg of 1 × 1 mL (880124X-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 880124X
• 濃度: 1 mg/mL (880124X-1mg); 10 mg/mL (880124X-10mg)
• 輸送温度: dry ice
• 保管温度: −20°C

詳細

詳細

DSPE-PEG(2000) Folate, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000], is a functionalized PEG lipid. This lipid is added into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for numerous solid tumors and myeloid leukemias. Folate targeted drug delivery is used an effective therapy for the treatment and imaging of various cancers and inflammatory diseases. Folate conjugates with low molecular weight and high binding affinity for folate receptors (FR) on cell surface deliver a variety of molecular complexes such as protein toxins, immune stimulants, chemotherapeutic agents, liposomes, nanoparticles, and imaging agents to pathologic cells without affecting normal tissues.

アプリケーション

DSPE-PEG(2000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000]) may be used in preparation of folate-conjugated liposomes and folate-modified microvesicles (MVs).

包装

5 mL Clear Glass Sealed Ampule (880124X-10mg)

5 mL Clear Glass Sealed Ampule (880124X-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H226,H302,H315,H319,H331,H336,H351,H361d,H371,H372
• 注意書き: P210 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P311
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3
• ターゲットの組織: Eyes,Central nervous system, Liver,Kidney, Respiratory system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 80.6 °F
• 引火点(℃): 27 °C