880120C

18:0 PEG2000 PE

Avanti Polar Lipids 880120C

• 別名: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
• CAS番号: 474922-77-5
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 形状: liquid
• 包装: pkg of 1 × 2.5 mL (880120C-25mg); pkg of 1 × 20 mL (880120C-500mg); pkg of 2 × 4 mL (880120C-200mg)
• メーカー／製品名: Avanti Polar Lipids 880120C
• 濃度: 10 mg/mL (880120C-25mg); 25 mg/mL (880120C-200mg); 25 mg/mL (880120C-500mg)
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

詳細

詳細

18:0 PEG2000 PE, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000], is a modified phospholipid containing a 2000-Da PEG moiety in the polar head.

アプリケーション

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt (DSPE-PEG1) has been used to conjugate PEG onto residual amine groups on the surfaces of the functionalized TaO nanoparticles. DSPE-PEG1 may be used as a surfactant for homeotropic anchoring of the mesogen molecules. It may also be used in preparation of Nano formulations.

生物化学的／生理学的作用

PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to facilitate the formation of sterically stabilized liposomes (SSL). These liposomes have low reticuloendothelial system (RES) uptake and they prolong the circulating plasma half-life of the drug. The plasma half-life of the drug can be tuned from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880120C-500mg)

5 mL Clear Glass Sealed Ampule (880120C-200mg)

5 mL Clear Glass Sealed Ampule (880120C-25mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412
• 注意書き: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 引火点(°F): does not flash
• 引火点(℃): does not flash