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アッセイ
>99% (TLC)
フォーム
powder
包装
pkg of 1 × 25 mg (840074P-25mg)
メーカー／製品名
Avanti Research™ - A Croda Brand 840074P
脂質タイプ
phosphoglycerides
輸送温度
dry ice
保管温度
−20°C
SMILES記法
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
詳細
Phosphatidic acid (PA) is a diacyl-glycerophospholipid, with two fatty acids and a phosphate group that are covalently attached to a glycerol molecule through ester linkages. PA is synthesized by the activity of the endogenous enzyme phospholipase D or by supplementation with soy lecithin.
アプリケーション
Soy PA is suitable for use to study its effect on cell proliferation, nutrient sensing and to examine metabolic pathways in primary muscle cells of turbot (Scophthalmus maximus).
生物化学的／生理学的作用
Phosphatidic acid (PA) is a prime glycerophospholipid present in the biomembrane and is a precursor for phosphatidylcholine or phosphatidylserine. It has different functions in the cells like influencing the membrane curvature and signaling.
包装
5 mL Clear Glass Sealed Ampule (840074P-25mg)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
No data available
引火点(℃)
No data available
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
840074P-VAR:
840074P-BULK:
840074P-25MG:
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The mitotic and metabolic effects of phosphatidic acid in the primary muscle cells of turbot (Scophthalmus maximus)
Wang T, et al.
Frontiers in Endocrinology, 9 (2018)
Daniel Schlam et al.
The Journal of biological chemistry, 288(32), 23090-23104 (2013-07-03)
It is commonly assumed that all phagosomes have identical molecular composition. This assumption has remained largely unchallenged due to a paucity of methods to distinguish individual phagosomes. We devised an assay that extends the utility of nitro blue tetrazolium for
Michal Bohdanowicz et al.
Molecular biology of the cell, 24(11), 1700-1712 (2013-04-12)
Macrophages and dendritic cells continuously survey their environment in search of foreign particles and soluble antigens. Such surveillance involves the ongoing extension of actin-rich protrusions and the consequent formation of phagosomes and macropinosomes. The signals inducing this constitutive cytoskeletal remodeling
Chi-Lun Chang et al.
The Journal of biological chemistry, 290(23), 14289-14301 (2015-04-19)
Phosphatidylinositol (PI) 4,5-bisphosphate (PIP2) at the plasma membrane (PM) constitutively controls many cellular functions, and its hydrolysis via receptor stimulation governs cell signaling. The PI transfer protein Nir2 is essential for replenishing PM PIP2 following receptor-induced hydrolysis, but key mechanistic
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