810211C

C12-NBD Ceramide

Avanti Research^™ - A Croda Brand 810211C

• 別名: N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine
• 実験式（ヒル表記法）: C₃₆H₆₁N₅O₆
• CAS番号: 202850-01-9
• 分子量: 659.90
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: liquid
• 包装: pkg of 1 × 1 mL (810211C-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 810211C
• 濃度: 1 mg/mL (810211C-1mg)
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCCCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO
• InChI: 1S/C36H61N5O6/c1-2-3-4-5-6-7-8-9-10-12-15-18-21-24-33(43)31(29-42)38-34(44)25-22-19-16-13-11-14-17-20-23-28-37-30-26-27-32(41(45)46)36-35(30)39-47-40-36/h21,24,26-27,31,33,37,42-43H,2-20,22-23,25,28-29H2,1H3,(H,38,44)/b24-21+/t31-,33+/m0/s1
• InChI Key: SNOJCYCOPNIGIK-ULETYAGTSA-N

詳細

アプリケーション

C12-NBD ceramide is suitable for its use:

• as a substrate to measure the activity of acid, alkaline and neutral ceramidases
• in in vitro ceramidase activity assay
• in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)

生物化学的／生理学的作用

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

包装

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302,H315,H319,H331,H336,H351,H361d,H372
• 注意書き: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• ターゲットの組織: Central nervous system
• WGK: WGK 3