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Merck

791275P

Avanti

18:0 PE-DTPA (Gd)

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt), powder

別名:

1,2-dioctadecanoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt); DSPE-DTPA (Gd)

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About This Item

実験式(ヒル表記法):
C55H106GdN6O17P
CAS番号:
分子量:
1311.68
UNSPSCコード:
12352211
NACRES:
NA.25

アッセイ

>99% (TLC)

形状

powder

包装

pkg of 1 × 5 mg (791275P-5mg)

メーカー/製品名

Avanti Polar Lipids 791275P

輸送温度

dry ice

保管温度

−20°C

関連するカテゴリー

詳細

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt) (18:0 PE-DTPA (Gd)) are sparing soluble in alcohol and well soluble in a solvent mixture consisting of chloroform and methanol in the ratio of 4:1, v/v. 18:0 PE-DTPA (Gd) is a synthetic phospholipid derivative ethanolamine. The DTPA is attached to gadolinium ion.

アプリケーション

18:0 PE-DTPA (Gd) has been used:
  • as a component of Gadolinium-liposome preparation
  • in the nanodics preparation for nuclear magnetic resonance (NMR) studies
  • in construction of cysteine-arginine-glutamic acid-lysine alanine (CREKA) based peptide amphiphile micelles (PAMs) for the magnetic resonance imaging (MRI) studies
  • as a spin-labeled lipid for supported lipid bilayer incorporation for cryo transmission electron microscopy studies

生物化学的/生理学的作用

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt) (18:0 PE-DTPA (Gd)) phospholipid based liposomes are useful in magnetic resonance imaging (MRI) and multimodal imaging. Apart from being a MRI contrast agent, PE-DTPA (Gd) liposome is also flexible for modification for binding different targets using copper–free click–chemistry methodology.

包装

5 mL Amber Glass Screw Cap Vial (791275P-5mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

保管分類コード

11 - Combustible Solids

WGK

WGK 3


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Fibrin-targeting, peptide amphiphile micelles as contrast agents for molecular MRI
Chung EJ, et al.
journal of Cell Science & Therapy, 5(5), 1-1 (2014)
Supported Lipid Bilayers on Fluorescent Nanodiamonds: A Structurally Defined and Versatile Coating for Bioapplications
Vavra J, et al.
Advances in Functional Materials, 28(45), 1803406-1803406 (2018)
Jin Young Kang et al.
Immunity, 31(6), 873-884 (2009-11-26)
Toll-like receptor 2 (TLR2) initiates potent immune responses by recognizing diacylated and triacylated lipopeptides. Its ligand specificity is controlled by whether it heterodimerizes with TLR1 or TLR6. We have determined the crystal structures of TLR2-TLR6-diacylated lipopeptide, TLR2-lipoteichoic acid, and TLR2-PE-DTPA
Zhenhao Fang et al.
Cell chemical biology, 25(11), 1327-1336 (2018-08-21)
KRAS is frequently mutated in several of the most lethal types of cancer; however, the KRAS protein has proven a challenging drug target. K-RAS4B must be localized to the plasma membrane by prenylation to activate oncogenic signaling, thus we endeavored

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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