699854P

4A-MPLA (isomer C3)

Avanti Research^™ - A Croda Brand

• 別名: Monophosphopdyl Tetra-acyl Lipid A
• 実験式（ヒル表記法）: C₆₈H₁₃₂N₃O₁₉P
• CAS番号: 2260669-09-6
• 分子量: 1326.76
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: >99% (HPLC)
• フォーム: powder
• 包装: pkg of 1 × 1 mg (699854P-1mg); pkg of 1 × 5 mg (699854P-5mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• アプリケーション: vaccine development
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2OC(C[C@H](O)CCCCCCCCCCC)=O.[NH4+]
• InChI: 1S/C68H129N2O19P.H3N/c1-5-9-13-17-21-25-26-30-34-38-42-46-59(76)85-54(45-41-37-33-29-24-20-16-12-8-4)49-58(75)69-61-64(79)65(89-90(81,82)83)55(50-71)87-68(61)84-51-56-63(78)66(88-60(77)48-53(73)44-40-36-32-28-23-19-15-11-7-3)62(67(80)86-56)70-57(74)47-52(
• InChI Key: KREAPURBNFKEHO-BNSRHSNQSA-N

詳細

生物化学的／生理学的作用

Structural modification of diphosphoryl lipid A by hydrolysis produces MPLA (monophosphoryl lipid A) and is known to decrease its toxicity. MPLA, a lipopolysaccharide derivative, acts an immunomodulator and is non-toxic. For this reason, it is useful as a vaccine adjuvant. The MPLA induced immune response is tissue specific. It enhances host′s resistance against endotoxin induced effects. It also decreases cytokine production during infection.

包装

2 mL Amber Glass Crimp Cap Vial (699854P-1mg)

2 mL Amber Glass Crimp Cap Vial (699854P-5mg)

その他情報

For R&D use only. Not for drug, household, or other uses.

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): No data available
• 引火点(℃): No data available