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品質水準
アッセイ
97%
形状
powder
反応適合性
reagent type: cross-linking reagent
mp
285-295 °C (lit.)
官能基
carboxylic acid
sulfonamide
SMILES記法
O=S(C(C=C1)=CC=C1C(O)=O)(N)=O
InChI
1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)
InChI Key
UCAGLBKTLXCODC-UHFFFAOYSA-N
遺伝子情報
human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238) , CA9(768)
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詳細
4-Sulfamoylbenzoic acid also known as 4-carboxybenzenesulfonamide, is a sulfonamide derivative of benzoic acid. It is a crosslinking reagent used widely in organic synthesis.
アプリケーション
4-Sulfamoylbenzoic acid is used to synthesize 4-sulfamoylbenzoyl chloride and isocyanate derivatives. Additionally, it can be used in the esterification of alcohols.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
C11804-VAR:
C11804-5G:
C11804-BULK:
C11804-10KG:
C11804-100G:
C11804-500G:
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Journal of medicinal chemistry, 48(6), 2121-2125 (2005-03-18)
Targeting proteins overexpressed in hypoxic tumors is as an important means of controlling cancer disease. One such protein is the carbonic anhydrase (CA) isoenzyme IX, which in some types of tumors is overexpressed 150-200-fold. We report here a series of
The American journal of physiology, 246(3 Pt 1), C242-C246 (1984-03-01)
The secretory response of isolated perfused shark rectal gland was characterized with respect to its inhibition by a chemically related series of 5-sulfamoylbenzoic acid derivatives and certain phenoxyacetic acid derivatives. Maximal fluid and salt secretion was elicited with dibutyryl adenosine
PloS one, 6(5), e20123-e20123 (2011-06-02)
Bitter taste stimuli are detected by a diverse family of G protein-coupled receptors (GPCRs) expressed in gustatory cells. Each bitter taste receptor (TAS2R) responds to an array of compounds, many of which are toxic and can be found in nature.
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To better understand disease conditions and environmental perturbations, multiomic studies combining proteomic, lipidomic, and metabolomic analyses are vastly increasing in popularity. In a multiomic study, a single sample is typically extracted in multiple ways, and various analyses are performed using
Bioorganic & medicinal chemistry letters, 15(4), 963-969 (2005-02-03)
The inhibition of a newly cloned human carbonic anhydrase (CA, EC 4.2.1.1), isozyme XII (hCA XII), has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide, dorzolamide, brinzolamide, benzolamide, and sulpiride, or indisulam
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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