900893

L-Homopropargylglycine hydrochloride

• 別名: HPG
• 実験式（ヒル表記法）: C₆H₉NO₂ · HCl
• CAS番号: 98891-36-2
• 分子量: 163.60
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• フォーム: powder or crystals
• 利用可能性: available only in USA
• mp: 162 °C
• 保管温度: −20°C
• SMILES記法: O=C(O[H])[C@@](C([H])([H])C([H])([H])C#C[H])([H])N([H])[H].Cl[H]
• InChI: 1S/C6H9NO2/c1-2-3-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)
• InChI Key: SCGJGNWMYSYORS-UHFFFAOYSA-N

詳細

アプリケーション

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click” reaction between an azide and an alkyne or cyclooctyne. For example the alkyne-modified protein can be detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

安全性情報

• ピクトグラム: GHS02
• シグナルワード: Danger
• 危険有害性情報: H242
• 注意書き: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危険有害性の分類: Self-react. C
• 保管分類コード: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable