317500

(1S,2R)-(+)-ノルエフェドリン

98%

• 別名: (1S,2R)-2-アミノ-1-フェニル-1-プロパノール, フェニルプロパノールアミン
• 化学式: C₆H₅CH(OH)CH(CH₃)NH₂
• CAS番号: 37577-28-9
• 分子量: 151.21
• Beilstein: 2802896
• MDL番号: MFCD00064411
• UNSPSCコード: 12352116
• PubChem Substance ID: 24859081
• NACRES: NA.22

特性

• 品質水準: 200
• アッセイ: 98%
• 形状: solid
• 光学活性: [α]20/D +40°, c = 7 in 1 M HCl
• mp: 51-54 °C (lit.)
• 官能基: amine; hydroxyl; phenyl
• 保管温度: 2-8°C
• SMILES記法: C[C@@H](N)[C@@H](O)c1ccccc1
• InChI: 1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1
• InChI Key: DLNKOYKMWOXYQA-VXNVDRBHSA-N

詳細

詳細

(1S,2R)-(+)-Norephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.

アプリケーション

(1S,2R)-(+)-Norephedrine may be used in the preparation of dendritic ligands, which on combining with Ru(II) complexes form efficient asymmetric transfer hydrogenation catalysts. It may also be used in the preparation of N-((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)furan-2-carboxamide. This chiral amide can efficiently catalyze the enantioselective ethylation of aromatic and heteroaromatic aldehydes to secondary alcohols in the absence of titanium tetraisopropoxide as promotor.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): 235.4 °F - closed cup
• 引火点(℃): 113 °C - closed cup
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves