PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
別名:
AMPK, AMPK2, AMPKa2, PRKAA
Species:
Human PRKAA2 (5563), Mouse Prkaa2 (108079), Rat Prkaa2 (78975), cow PRKAA2 (538954), sheep PRKAA2 (100127210), domestic guinea pig Prkaa2 (100713170), naked mole-rat Prkaa2 (101698482), Zebrafish prkaa2 (572074), Horse PRKAA2 (100034159), domestic cat PRKAA2 (101096000) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5563) Summary: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
- Mouse(108079) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Rat(78975) protein kinase, AMP-activated, alpha 2 catalytic subunit
- cow(538954) protein kinase, AMP-activated, alpha 2 catalytic subunit
- sheep(100127210) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic guinea pig(100713170) protein kinase, AMP-activated, alpha 2 catalytic subunit
- naked mole-rat(101698482) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Zebrafish(572074) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Horse(100034159) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic cat(101096000) protein kinase, AMP-activated, alpha 2 catalytic subunit
- chicken(429110) protein kinase, AMP-activated, alpha 2 catalytic subunit
- dog(489571) protein kinase, AMP-activated, alpha 2 catalytic subunit
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗リン酸化AMPKα (Thr172)抗体 クローン5J23 ZooMAb® ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anti-AMPK alpha 1/2 Antibody, clone 34.2, clone 34.2, from mouse,
交差性
drosophila, human, mouse, rat
アプリケーション
western blot
Anti-PRKAA2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, canine, human, mouse, rabbit, rat
アプリケーション
ELISA
western blot
western blot
Anti-PRKAA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
製品番号
詳細
Species
AMPK (α2, β1, γ1) Protein, active, 10 µg, Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
Species
human
AMPK (α2/β2/γ1)、活性型、Hisタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK (α2/β2/γ1)、活性型、Hisタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
製品番号
詳細
Species