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CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

別名:
CAMKA
Species:
UniProtKB ID:
遺伝子ID:
  • Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
  • Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
  • Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
  • Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
  • naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
  • domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
  • Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
  • chicken(374175) calcium/calmodulin-dependent protein kinase II alpha
  • dog(612941) calcium/calmodulin-dependent protein kinase II alpha
  • cow(530719) calcium/calmodulin-dependent protein kinase II alpha
  • Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
  • domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha

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Small Molecule - Antagonist

製品番号
詳細
Species
N-(6-アミノヘキシル)-5-クロロ-1-ナフタレンスルホンアミド 塩酸塩, ,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
抗CaMキナーゼII抗体、αサブユニット、クローン6G9, clone 6G9, Upstate®, from mouse,
交差性
bovine, rat
アプリケーション
immunohistochemistry
western blot
Anti-CAMK2 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
モノクローナル抗CaM キナーゼIIα(CaMKIIα)抗体 マウス宿主抗体, clone 6G9, purified immunoglobulin, buffered aqueous solution,
交差性
mouse, rat
アプリケーション
immunofluorescence
western blot
Monoclonal Anti-CAMK2A antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot
Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1, clone 22B1, Upstate®, from mouse,
交差性
rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
アデニン, ≥99%,
Species
human, rat, mouse
アデニン, BioReagent, suitable for cell culture,
Species
human, rat, mouse
アデニン, BioReagent, suitable for plant cell culture, ≥99%,
Species
human, rat, mouse

Proteins

製品番号
詳細
Species
CAMK2α、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
カルモジュリン依存性プロテインキナーゼIIフラグメント 290-309, ≥97% (HPLC),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CAMK2A,
Species
human
MISSION® esiRNA, targeting mouse Camk2a,
Species
mouse

Small Molecule - Substrate

製品番号
詳細
Species
オートカムチド2関連抑制性ペプチド, ≥97% (HPLC), lyophilized powder,
Species
mouse, rat, human