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914134

Sigma-Aldrich

5-(Biotinamido)pentylamine TFA Salt

≥95%

Synonym(s):

N-(5-Aminopentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pent, Biotin cadaverine TFA, Biotin-DAPe TFA

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About This Item

Empirical Formula (Hill Notation):
C15H28N4O2S · xC2HF3O2
Molecular Weight:
328.47 (free base basis)
MDL number:
MFCD03452814
UNSPSC Code:
12352116
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

powder

mp

116-121 °C

storage temp.

2-8°C

Application

5-(Biotinamido)pentylamine TFA Salt is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Site-selective conversion of azido groups at carbonyl α-positions into oxime groups leading triazide to a triple click conjugation scaffold

Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions

Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation

Synthesis of Novel Phosphonic-Type Activity-Based Probes for Neutrophil Serine Proteases and Their Application in Spleen Lysates of Different Organisms

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

914134-VAR:
914134-BULK:
914134-250MG:

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Sung Kook Chun et al.
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Marianne van Wyk et al.
Chemical communications (Cambridge, England), (4), 398-400 (2007-01-16)
Coenzyme A analogues are synthesized in a one-pot preparation by biotransformation of pantothenate thioesters through the simultaneous use of three CoA biosynthetic enzymes, followed by aminolysis.
Taiki Yokoi et al.
Chemical communications (Cambridge, England), 55(13), 1891-1894 (2018-12-21)
This paper reports the selective conversion of alkyl azido groups at the carbonyl α-position into oximes through β-elimination of dinitrogen, followed by transoximation. With this method and diazo conversion, a triazido molecule was transformed into a triple click conjugation scaffold
Collette S Guy et al.
Organic & biomolecular chemistry, 17(43), 9524-9528 (2019-10-30)
Dimeric benzoboroxoles that are covalently linked by a short scaffold enhance selective anti-tubercular activity. These multimeric benzoboroxole compounds are capable of engaging the specific extracellular Mycobacterium tuberculosis glycans, do not lead to the evolution of resistance and bypass the need
Aoi Teraoka et al.
Chemical communications (Cambridge, England), 50(6), 664-666 (2013-11-28)
A facile and useful method for preparing caged DNAs was developed. The method includes a caging reaction of a linear dsDNA having a minimal sequence of protein expression with Bio-Bhc-diazo and affinity separation of the caged DNA. Effective suppression and
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