Merck
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1265515

USP

Ethylene glycol

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
Ethylene glycol, 1,2-Ethanediol
Linear Formula:
HOCH2CH2OH
CAS Number:
107-21-1
Molecular Weight:
62.07
Beilstein:
505945
MDL number:
MFCD00002885
PubChem Substance ID:
329749793
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

2.1 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

autoignition temp.

752 °F

expl. lim.

15.3 %

manufacturer/tradename

USP

refractive index

n20/D 1.431 (lit.)

bp

195-198 °C

mp

−13 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.
Sales restrictions may apply.

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

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Quotes and Ordering

Bulk Quote-Order Product
Peter Mygind Leth et al.
Forensic science international, 155(2-3), 179-184 (2005-10-18)
Ethylene glycol (EG) can be found in many agents, such as antifreeze. Ingestion of EG may cause serious poisoning. Adults are typically exposed when EG is ingested as a cheap substitute for ethanol or in suicide-attempts. Children may be exposed
Eurwin Suryana et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 37, 69-75 (2014-07-11)
Myelination is an essential process in human development that is carried out by oligodendrocytes in the central nervous system. Hypoxic-ischaemic (HI) brain injury can disrupt myelination by causing oxidative stress, inflammation and excitotoxicity, resulting in the loss of myelin as
Robert Hess et al.
Archives of toxicology, 78(12), 671-680 (2004-09-17)
Upon ingestion ethylene glycol (EG, monoethylene glycol) is rapidly absorbed from the gastrointestinal tract, and depending on the severity of exposure signs of toxicity may progress through three stages. Neurological effects characterize the first step consisting of central nervous depression
Frank F J Simonis et al.
Magnetic resonance in medicine, 73(3), 1184-1189 (2014-03-26)
MR thermometry (MRT) is a noninvasive method for measuring temperature that can potentially be used for radio frequency (RF) safety monitoring. This application requires measuring absolute temperature. In this study, a multigradient-echo (mGE) MRT sequence was used for that purpose.
Sukonthar Ngampramuan et al.
Oncotarget, 5(6), 1565-1575 (2014-04-15)
Nausea is a prominent symptom and major cause of complaint for patients receiving anticancer chemo- or radiation therapy. The arsenal of anti-nausea drugs is limited, and their efficacy is questionable. Currently, the development of new compounds with anti-nausea activity is
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