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Key Documents

Altri documenti

1362103

USP

Levofloxacin

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

Levofloxacin hemihydrate

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About This Item

Formula empirica (notazione di Hill):
C18H20FN3O4 · 0.5H2O
Numero CAS:
138199-71-0
Peso molecolare:
370.38
Numero MDL:
MFCD07772024
Codice UNSPSC:
41116107
ID PubChem:
329750045
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

levofloxacin

Produttore/marchio commerciale

USP

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4C(=O)C(=CN1c24)C(O)=O.C[C@H]5COc6c(N7CCN(C)CC7)c(F)cc8C(=O)C(=CN5c68)C(O)=O

InChI

1S/2C18H20FN3O4.H2O/c2*1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h2*7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H2/t2*10-;/m00./s1
SUIQUYDRLGGZOL-RCWTXCDDSA-N

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Categorie correlate

Applicazioni

Levofloxacin USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Levofloxacin Tablets
  • Levofloxacin Oral Solution

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
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Levofloxacin Related Compound A, United States Pharmacopeia (USP) Reference Standard

1362125

Levofloxacin Related Compound B, United States Pharmacopeia (USP) Reference Standard

1362136

Levofloxacin Related Compound C, United States Pharmacopeia (USP) Reference Standard

1362169

Levofloxacin Related Compound F, United States Pharmacopeia (USP) Reference Standard

1362158

Levofloxacin Related Compound E, United States Pharmacopeia (USP) Reference Standard

Y0002085

Levofloxacin hemihydrate, European Pharmacopoeia (EP) Reference Standard

Y0002084

Levofloxacin impurity F, European Pharmacopoeia (EP) Reference Standard

Y0002089

Levofloxacin for system suitability, European Pharmacopoeia (EP) Reference Standard

PHR2229

Levofloxacin Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2230

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Pittogrammi

Exclamation markHealth hazard
GHS07,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H302 - H317 - H334

Classi di pericolo

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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R Davis et al.
Drugs, 47(4), 677-700 (1994-04-01)
Levofloxacin, an oral fluoroquinolone antibacterial agent, is the optical S-(-) isomer of ofloxacin. In vitro it is generally twice as potent as ofloxacin. Levofloxacin is active against most aerobic Gram-positive and Gram-negative organisms and demonstrates moderate activity against anaerobes. Drug
Analysis and Standardization of Levofloxacin Substance.
Sedova, M. K., et al.
Pharmaceutical Chemistry Journal, 47.11, 620-626 (2014)
Kyung Eun Han et al.
American journal of ophthalmology, 157(6), 1144-1150 (2014-02-25)
To evaluate dry eye and meibomian gland dysfunction after cataract surgery. Prospective observational case series. We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores
Lixian He et al.
Anti-cancer drugs, 26(3), 359-362 (2014-12-09)
This pilot study assesses the safety and efficacy of once-daily, oral levofloxacin monotherapy in Chinese patients with low-risk febrile neutropenia. In this prospective, single-arm, open-label, multicenter clinical trial, 46 adult Chinese patients with solid tumors and low-risk febrile neutropenia were
Sabine Schuster et al.
Antimicrobial agents and chemotherapy, 58(11), 6870-6878 (2014-09-04)
Efflux is an important mechanism of bacterial multidrug resistance (MDR), and the inhibition of MDR pumps by efflux pump inhibitors (EPIs) could be a promising strategy to overcome MDR. 1-(1-Naphthylmethyl)-piperazine (NMP) and phenylalanine-arginine-β-naphthylamide (PAβN) are model EPIs with activity in
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