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40922

Supelco

Levofloxacin

analytical standard

Sinonimo/i:

(−)-Ofloxacin

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About This Item

Formula empirica (notazione di Hill):
C18H20FN3O4
Numero CAS:
100986-85-4
Peso molecolare:
361.37
Beilstein:
7327015
Numero MDL:
MFCD00865049
Codice UNSPSC:
41116107
ID PubChem:
329756033
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Attività ottica

[α]20/D -104±4° in chloroform

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

clinical testing

Formato

neat

Stringa SMILE

OC(C(C1=O)=CN2C(C1=CC(F)=C3N4CCN(C)CC4)=C3OC[C@@H]2C)=O

InChI

1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
GSDSWSVVBLHKDQ-JTQLQIEISA-N

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Categorie correlate

Descrizione generale

Chemical structure: quinolone

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H317,H334

Classi di pericolo

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCF6845
BCCC8993
BCCB4788
BCBX0878
BCBW2333

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Levofloxacin Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2229

Levofloxacin Related Compound B

Levofloxacin impurity F European Pharmacopoeia (EP) Reference Standard

Y0002084

Levofloxacin impurity F

Levofloxacin Related Compound A United States Pharmacopeia (USP) Reference Standard

USP

1362114

Levofloxacin Related Compound A

Ciprofloxacin VETRANAL®, analytical standard

Supelco

33434

Ciprofloxacin

Moxifloxacin hydrochloride VETRANAL®, analytical standard

Supelco

32477

Moxifloxacin hydrochloride

Orbifloxacin VETRANAL®, analytical standard

Supelco

34041

Orbifloxacin

Moxifloxacin hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML1581

Moxifloxacin hydrochloride

Abrar K Thabit et al.
International journal of antimicrobial agents, 48(5), 535-541 (2016-11-05)
Increasing antimicrobial resistance in community-acquired pneumonia (CAP) pathogens has contributed to infection-related morbidity and mortality. Delafloxacin is a novel fluoroquinolone with broad-spectrum activity against Gram-positive and -negative organisms, including Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus (MRSA). This study aimed to
John S Bradley et al.
Pediatrics, 134(1), e146-e153 (2014-06-12)
Safety concerns for fluoroquinolones exist from animal studies demonstrating cartilage injury in weight-bearing joints, dependent on dose and duration of therapy. For children treated with levofloxacin or comparator in randomized, prospective, comparative studies for acute otitis media and community-acquired pneumonia
Hans H Liu
Drug safety, 33(5), 353-369 (2010-04-20)
The fluoroquinolone class of antibacterial agents are among the most frequently prescribed drugs, with utility in a broad range of bacterial infections. Although very useful agents, the fluoroquinolones as a class are associated with a number of adverse events, some
Vanessa R Anderson et al.
Drugs, 68(4), 535-565 (2008-03-06)
Levofloxacin (Levaquin) is a fluoroquinolone antibacterial that is the L-isomer of ofloxacin. A high-dose (750 mg) short-course (5 days) of once-daily levofloxacin is approved for use in the US in the treatment of community-acquired pneumonia (CAP), acute bacterial sinusitis (ABS)
Won-Jung Koh et al.
American journal of respiratory and critical care medicine, 188(7), 858-864 (2013-08-10)
Levofloxacin (LFX) and moxifloxacin (MXF) are the two most frequently recommended fluoroquinolones for treatment of patients with multidrug-resistant tuberculosis (MDR-TB). However, studies comparing the effectiveness of LFX and MXF among patients with MDR-TB are lacking. To compare the effectiveness of
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