T4626

N_α-p-Tosyl-L-arginine methyl ester hydrochloride

≥98% (TLC), suitable for ligand binding assays

• Sinonimo/i: TAME hydrochloride
• Formula condensata: H₂NC(=NH)NH(CH₂)₃CH(NHSO₂C₆H₄CH₃)CO₂CH₃ · HCl
• Numero CAS: 1784-03-8
• Peso molecolare: 378.87
• Beilstein: 3922357
• Numero CE: 217-235-1
• Numero MDL: MFCD00012578
• Codice UNSPSC: 12352103
• eCl@ss: 32160406
• ID PubChem: 24900058
• NACRES: NA.26

Proprietà

• Nome del prodotto: N_α-p-Tosyl-L-arginine methyl ester hydrochloride,
• Saggio: ≥98% (TLC)
• Livello qualitativo: 200
• Stato: powder
• tecniche: ligand binding assay: suitable
• Colore: white
• Punto di fusione: 145-147 (lit.)
• Temperatura di conservazione: −20°C
• Stringa SMILE: Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1
• InChI: 1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1; JIQFFACVQXXHMY-YDALLXLXSA-N

Descrizione

Applicazioni

Nα-p-Tosyl-L-arginine methyl ester hydrochloride has been used as an esterolytic substrate to assess trypsin-like activity in midgut extracts. It has also been used as a substrate for measuring trypsin activity of pancreatin and human intestinal samples.

Azioni biochim/fisiol

N_α-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1.

Substrati

Substrate for trypsin, thrombin, plasmin, and other proteases.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)