P4380
Protamine sulfate
powder
Sinonimo/i:
Salmine, Salmine from salmon
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About This Item
Prodotti consigliati
Nome del prodotto
Protamine sulfate salt from salmon, Grade II
Origine biologica
fish (salmon)
Livello qualitativo
Tipo
Grade II
Stato
powder
Colore
white to off-white
Solubilità
6 M HCl: 25 mg/mL, clear, colorless to light yellow
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Descrizione generale
Protamine sulfate (PS), a polycationic, positively charged protein is mostly made up of poly(l-arginine). It is obtained from salmon sperm protein.
Applicazioni
May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate salt from salmon has been used in the generation of protamine silica nanocomposites.
Azioni biochim/fisiol
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.
Protamine sulfate is highly preferred in cardiovascular surgical procedures to reverse the anticoagulant properties of heparin. It is used for biomedical and biotechnological applications due to its biodegradablity.
Qualità
May contain insolubles as well as histones.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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