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Key Documents

L7381

Sigma-Aldrich

Lectina da Arachis hypogaea (arachide)

FITC conjugate, lyophilized powder

Sinonimo/i:

Agglutinina dell’arachide, PNA

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About This Item

Codice UNSPSC:
12352202
NACRES:
NA.32

Coniugato

FITC conjugate

Livello qualitativo

Forma fisica

lyophilized powder

Composizione

Protein, ~10% Lowry

Grado di funzionalizzazione

4-8 mol FITC per mol protein

Temperatura di conservazione

−20°C

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Descrizione generale

Lectins are carbohydrate-binding proteins, omnipresent, found in fungi, plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in β-strands and possesses a carbohydrate binding sites on the surface.

Applicazioni

Lectin from Arachis hypogaea (peanut) has been used:
  • to determine the acrosomal status (presence or absence of acrosomal matrix corresponding to intact or acrosome-reacted spermatozoa) on viable sperm cells
  • to probe cryosections of mediastinal lymph nodes (mLNs) with fluorochrome-labeled PNA and anti-B220 to detect germinal centers (GCs)
  • to visualize the cone outer segments of pre-treated retinal sections

Azioni biochim/fisiol

Lectin is known to be useful in glycoconjugate characterizing, imaging and targeting. Its use in a microarray assay, enable efficient glycome profiling. This is because of its specific interaction with oligosaccharides, glycoproteins and glycolipids. In plants and fungi, lectin defends against pathogens/feeders. Lectin participates in host recognition and tissue adhesion, thereby aids in the pathogenesis of microorganism.
La PNA non fa agglutinare gli eritrociti umani normali, ma fa agglutinare fortemente gli eritrociti trattati con la neuraminidasi. La PNA esercita una potente attività anti-T analogamente all′anticorpo anti-T nei sieri umani. La lectina può essere utilizzata per distinguere i sottoinsiemi di linfociti umani.

Stato fisico

Contains phosphate buffer salts and NaCl

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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