L7381
Lectina da Arachis hypogaea (arachide)
FITC conjugate, lyophilized powder
Sinonimo/i:
Agglutinina dell’arachide, PNA
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About This Item
Codice UNSPSC:
12352202
NACRES:
NA.32
Prodotti consigliati
Coniugato
FITC conjugate
Livello qualitativo
Stato
lyophilized powder
Composizione
Protein, ~10% Lowry
Grado di funzionalizzazione
4-8 mol FITC per mol protein
Temperatura di conservazione
−20°C
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Descrizione generale
Lectins are carbohydrate-binding proteins, omnipresent, found in fungi, plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in β-strands and possesses a carbohydrate binding sites on the surface.
Applicazioni
Lectin from Arachis hypogaea (peanut) has been used:
- to determine the acrosomal status (presence or absence of acrosomal matrix corresponding to intact or acrosome-reacted spermatozoa) on viable sperm cells
- to probe cryosections of mediastinal lymph nodes (mLNs) with fluorochrome-labeled PNA and anti-B220 to detect germinal centers (GCs)
- to visualize the cone outer segments of pre-treated retinal sections
Azioni biochim/fisiol
La PNA non fa agglutinare gli eritrociti umani normali, ma fa agglutinare fortemente gli eritrociti trattati con la neuraminidasi. La PNA esercita una potente attività anti-T analogamente all′anticorpo anti-T nei sieri umani. La lectina può essere utilizzata per distinguere i sottoinsiemi di linfociti umani.
Lectin is known to be useful in glycoconjugate characterizing, imaging and targeting. Its use in a microarray assay, enable efficient glycome profiling. This is because of its specific interaction with oligosaccharides, glycoproteins and glycolipids. In plants and fungi, lectin defends against pathogens/feeders. Lectin participates in host recognition and tissue adhesion, thereby aids in the pathogenesis of microorganism.
Stato fisico
Contains phosphate buffer salts and NaCl
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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