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Documenti fondamentali

L2643

Sigma-Aldrich

α-Lactose monohydrate

suitable for cell culture, BioReagent

Sinonimo/i:

β-D-Gal-(1→4)-α-D-Glc, 4-O-β-D-Galactopyranosyl-α-D-glucose, Milk sugar

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About This Item

Formula empirica (notazione di Hill):
C12H22O11 · H2O
Numero CAS:
Peso molecolare:
360.31
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.75

Origine biologica

bovine milk

Livello qualitativo

Nome Commerciale

BioReagent

Saggio

≥99% total lactose basis (GC)

Stato

powder

tecniche

cell culture | mammalian: suitable

Impurezze

≤0.05% Glucose
≤4% β-lactose

Solubilità

water: 100 mg/mL, clear, colorless

Stringa SMILE

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
WSVLPVUVIUVCRA-KPKNDVKVSA-N

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Applicazioni

α-Lactose monohydrate has been used:
  • as a component of fraction B of diluent M1 for dilution of ram semen
  • as a component of Platz diluent variant (PDV) for dilution of bottlenose dolphin semen
  • in the preparation of HyQ PF-Chinese hamster ovary (CHO) disaccharide media for the adaptation of CHO cell lines
  • for the preparation of protein-free chemically defined cell culture medium (PFCDM) for the adaptation of human embryonic kidney 293 (HEK293) cells

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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D-lattosio tested according to Ph. Eur.

Sigma-Aldrich

61341

D-lattosio

Anhydrous lactose United States Pharmacopeia (USP) Reference Standard

USP

1356676

Anhydrous lactose

D-lattosio European Pharmacopoeia (EP) Reference Standard

Y0001750

D-lattosio

D-lattosio Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1024

D-lattosio

Lactose, Anhydrous Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1025

Lactose, Anhydrous

A Thiel et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 528-539 (2019-02-06)
3-NOP (3-nitrooxypropanol) reduces enteric methane formation in ruminants. A series of ADME studies in rats, lactating goats and beef cattle was performed. 3-NOP was entirely absorbed from the GIT of rats: approximately 75% of the administered 3-NOP was eliminated as
T R Robeck et al.
Biology of reproduction, 70(5), 1340-1348 (2004-01-09)
Research was conducted to develop an effective method for cryopreserving bottlenose dolphin (Tursiops truncatus) semen processed immediately after collection or after 24-h liquid storage. In each of two experiments, four ejaculates were collected from three males. In experiment 1, three
Ling Zhang et al.
Theranostics, 10(24), 11339-11358 (2020-10-13)
Background: TSTA3 gene encodes an enzyme responsible for synthesis of GDP-L-fucose as the only donor in fucosylation. This study was designed to explore clinical value, function and underlying mechanism of TSTA3 in the development of esophageal squamous cell carcinoma (ESCC).
Dawn Sow Zong Leong et al.
Scientific reports, 7, 45216-45216 (2017-03-31)
Mammalian cells are generally considered to be unable to utilize polysaccharides for cell growth because the phospholipid bilayer in the cell membrane has very low permeability to sugars. With the recent discovery of the only known animal disaccharide transporter, a
Johannes Gursch et al.
Journal of pharmaceutical sciences, 104(10), 3481-3489 (2015-07-07)
Over the last years, continuous manufacturing has created significant interest in the pharmaceutical industry. Continuous filtration at low flow rates and high solid loadings poses, however, a significant challenge. A commercially available, continuously operating, dynamic cross-flow filtration device (CFF) is

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