Passa al contenuto
Merck
Tutte le immagini(2)

Documenti fondamentali

Visualizza tutta la documentazione

H5002

Sigma-Aldrich

17α-Hydroxypregnenolone

Sinonimo/i:

3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(2)

About This Item

Formula empirica (notazione di Hill):
C21H32O3
Numero CAS:
387-79-1
Peso molecolare:
332.48
Numero CE:
206-862-6
Numero MDL:
MFCD00021129
Codice UNSPSC:
41116107
ID PubChem:
24895665
NACRES:
NA.77

Livello qualitativo

100

Stringa SMILE

C[C@]1(CC[C@H](O)C2)C2=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(C(C)=O)O

InChI

1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3
JERGUCIJOXJXHF-UHFFFAOYSA-N

Descrizione generale

17α-hydroxypregnenolone is a derived from pregnenolone.

Applicazioni

17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.

Azioni biochim/fisiol

17α-hydroxypregnenolone acts as a precursor for cortisol and sex steroids.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Canrenone ≥97% (HPLC)

Sigma-Aldrich

SML1497

Canrenone

Pregnenolone Avanti Research™ - A Croda Brand

Avanti

700142P

Pregnenolone

21-Deoxycortisol

Sigma-Aldrich

P9521

21-Deoxycortisol

Dehydroisoandrosterone 3-sulfate sodium salt dihydrate ≥93% (TLC), powder

Sigma-Aldrich

D5297

Dehydroisoandrosterone 3-sulfate sodium salt dihydrate

Estrone ≥99%

Sigma-Aldrich

E9750

Estrone

21-Hydroxyprogesterone ≥97% (HPLC)

Sigma-Aldrich

D6875

21-Hydroxyprogesterone

4-Androsten-11β-ol-3,17-dione

Sigma-Aldrich

A3009

4-Androsten-11β-ol-3,17-dione

DHEA Avanti Research™ - A Croda Brand

Avanti

700087P

DHEA

Shogo Haraguchi et al.
Endocrinology, 153(2), 794-805 (2011-12-01)
7α-Hydroxypregnenolone (7α-OH PREG) is a newly identified bioactive neurosteroid stimulating locomotor activity in the brain of newt, a wild animal, which serves as an excellent model to investigate the biosynthesis and biological action of neurosteroids. Here, we show that acute
Kazuyoshi Tsutsui et al.
General and comparative endocrinology, 168(2), 275-279 (2010-02-09)
We now know that steroids can be synthesized de novo by the brain and the peripheral nervous system. Such steroids are called neurosteroids and de novo neurosteroidogenesis from cholesterol is a conserved property of vertebrate brains. Our studies over the
Kazuyoshi Tsutsui et al.
General and comparative endocrinology, 176(3), 440-447 (2011-12-06)
Seasonally-breeding amphibians have served as excellent animal models to investigate the biosynthesis and biological actions of neurosteroids. Previous studies have demonstrated that the brain of amphibians possesses key steroidogenic enzymes and produces pregnenolone, a precursor of steroid hormones, and other
Tamara S Hannon et al.
Journal of pediatric and adolescent gynecology, 25(1), 82-85 (2011-11-18)
Little is known about racial differences in androgen levels among obese children. The objective of this pilot study was to compare basal and stimulated androgen levels in a cross-sectional sample of obese black and white pubertal females. STUDY DESIGN, SETTING
Teppei Koyama et al.
Annals of the New York Academy of Sciences, 1163, 444-447 (2009-05-22)
We recently identified 7alpha-hydroxypregnenolone as a novel amphibian neurosteroid stimulating locomotor activity in newts. Because male newts show marked diurnal changes in locomotor activity, we hypothesized that 7alpha-hydroxypregnenolone may be a key factor for the induction of diurnal changes in
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.