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Key Documents

G3126

Sigma-Aldrich

L-glutammina

≥99% (HPLC), ReagentPlus®

Sinonimo/i:

5-ammide dell’acido L-glutammico, Acido (S)-2,5-diammino-5-ossopentanoico, Levoglutamide

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About This Item

Formula condensata:
H2NCOCH2CH2CH(NH2)CO2H
Numero CAS:
Peso molecolare:
146.14
Beilstein:
1723797
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

product name

L-glutammina,

Livello qualitativo

Punto di fusione

185 °C (dec.) (lit.)

Stringa SMILE

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
ZDXPYRJPNDTMRX-VKHMYHEASA-N

Informazioni sul gene

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Descrizione generale

L-Glutamine is a versatile amino acid that plays an essential role in various metabolic processes within the human body. This non-essential amino acid is naturally abundant and contributes significantly to several vital functions. One of its primary functions is acting as the primary carrier of nitrogen in the body. It serves as the transport vehicle for nitrogen, which is a fundamental building block for many biological processes. Additionally, L-Glutamine is a major energy source for numerous types of cells, ensuring they have the energy they need to function optimally.

Moreover, L-Glutamine is essential for maintaining a delicate balance of ammonia in the body. This balance is crucial for preventing toxic ammonia levels. This amino acid facilitates the conversion of glutamic acid to glutamine, a process central to ammonia regulation. L-Glutamine is not only involved in nitrogen transport and energy production but also serves as a key player in various metabolic pathways. It participates in the biosynthesis of proteins, similar to other amino acids. Furthermore, it plays a significant role in the synthesis of urea and purines, vital components for nucleic acid production. L-Glutamine is also a vital resource for generating cellular energy, working closely with glucose for this purpose.

Another essential function of L-Glutamine is its contribution to nitrogen donation for multiple anabolic processes. These processes are vital for building crucial molecules, including purines, which are crucial for DNA production. This amino acid also provides carbon, replenishing the citric acid cycle, a central process in energy production within cells. L-Glutamine is a critical amino acid, acting as a nitrogen carrier, energy source, and contributing to protein synthesis and ammonia regulation. Its versatile functions make it a molecule of significant interest in the fields of cell biology, biochemical research, and metabolomics investigations.

Applicazioni

L-Glutamine has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.It has also been used to study non-enzymatic gluconeogenesis.

Azioni biochim/fisiol

L-glutamine is the most abundant amino acid in the body. It is essential for the synthesis of L-asparagine. L-glutamic acid aids the incorporation of NH4+ into biomolecules.
La L-glutammina è un amminoacido essenziale oltre che un componente fondamentale dei terreni di coltura e costituisce un′importante fonte di energia per le cellule coltivate. La L-glutammina è molto stabile in forma di polvere secca e di soluzione congelata. Tuttavia, nei terreni liquidi e nelle soluzioni madri, la L-glutammina si degrada con relativa rapidità. Per una resa ottimale delle cellule è generalmente necessaria l′integrazione dei terreni di coltura con la L-glutammina prima dell′uso.

Caratteristiche e vantaggi

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

Altre note

For additional information on our range of Biochemicals, please complete this form.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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L-Asparagine ≥98% (HPLC)

Sigma-Aldrich

A0884

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D-Glutamine ≥98% (HPLC)

Sigma-Aldrich

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L-glutammina Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1125

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L-glutammina 200 mM, Hybri-Max™, sterile-filtered, suitable for hybridoma

Sigma-Aldrich

G2150

L-glutammina

The Natural Health Dictionary: Your comprehensive A-to Z guide for healing with herbs, nutrition, supplements, and secret remedies (2011)
Lehninger Principles of Biochemistry Edition 4th (2005)
Advances in Food and Nutrition Research, 58-58 (1917)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature, 1-36 (2017)
Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice.
Messner CB
Proceedings of the National Academy of Sciences of the USA, 114(28), 7403-7407 (2017)

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