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D8821

Sigma-Aldrich

Dextran from Leuconostoc mesenteroides

average mol wt 60,000-76,000

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About This Item

Formula condensata:
(C6H10O5)n
Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201
NACRES:
NA.25

Origine biologica

bacterial (Leuconostoc mesenteroides)

Livello qualitativo

Forma fisica

powder

Attività ottica

[α]20/D 190 to 201 °, c = 2% (w/v) in water

PM

average mol wt 60,000-76,000

Colore

white to off-white

Punto di fusione

483  °C ((901 °F ))

Solubilità

water: 100 mg/mL at 25 °C, colorless to faintly yellow

Temperatura di conservazione

2-8°C

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
FZWBNHMXJMCXLU-UHFFFAOYSA-N

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Descrizione generale

Dextran is an extracellular bacterial polymer of D-glucopyranose. It consists of α-(1→6) linkage in the main chain with a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages. Dextran from L. mesenteroides B512F comprises 95% of α- (1→6) linkages and 5% of α-(1→3) branch linkages. Insoluble dextran from L. mesenteroides 1299 contains 63% α-(1→6), 27% of α-(1→2) and 8% of α-(1→3) linkages.

Applicazioni

Dextran from Leuconostoc mesenteroides has been used:
  • in resuspension of pellets and in Hanks′ balanced salt solution (HBSS) for the isolation of vascular nuclei from frozen post-mortem brain tissue
  • to prepare dextran solution in phosphate buffer saline and to maintain corneal hydration and restore corneal thickness to physiological levels of human eyes
  • as a polymer solution in the in situ aqueous two-phase systems (ATPS) formation with lysozyme PEGylation reaction

Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Azioni biochim/fisiol

Dextran is commercially available as a drug, especially as a blood plasma volume expander. This bacterial polysaccharide has several applications, such as adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Dextran is used in the thickening of jam and ice cream in the food industry. It prevents sugar crystallization and retains moisture. This helps in preserving the flavor and appearance of several food items.

Altre note

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2


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