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C8261

Sigma-Aldrich

Sodium chenodeoxycholate

≥97%

Sinonimo/i:

3α,7α-Dihydroxy-5β-cholanic acid, 5β-Cholanic acid-3α,7α-diol, Chenodeoxycholic acid sodium salt, Chenodesoxycholic acid, Chenodiol

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About This Item

Formula empirica (notazione di Hill):
C24H39NaO4
Numero CAS:
2646-38-0
Peso molecolare:
414.55
Numero MDL:
MFCD00065452
Codice UNSPSC:
12161900
ID PubChem:
24893037
NACRES:
NA.25

Descrizione

anionic

Livello qualitativo

200

Saggio

≥97%

Forma fisica

powder

PM

414.55 g/mol

tecniche

protein purification: suitable

Stringa SMILE

[Na].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])CC[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O4.Na.H/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);;/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;;/m1../s1
WANBNZVOEKGHSS-VQNKLXGESA-N

Descrizione generale

Sodium chenodeoxycholate is a bile salt, which has been shown to accelerate colonic transit and improve bowel function.

Applicazioni

Sodium chenodeoxycholate has been used in a study to assess DNA repair response in the bacterium Escherichia coli. It has also been used in a study to investigate the physical and chemical factors influencing germination of Clostridium difficile spores.

Azioni biochim/fisiol

Bile Salt

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301,H361d

Classi di pericolo

Acute Tox. 3 Oral - Repr. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

C9282

Colato di Sodio

Cholic Acid, Sodium Salt Primary bile acid.

Millipore

229101

Cholic Acid, Sodium Salt

Desossicolato di sodio An ionic detergent for the solubilization of membrane-bound proteins.

Millipore

264101

Desossicolato di sodio

Colato di Sodio BioXtra, ≥99%

Sigma-Aldrich

C6445

Colato di Sodio

Ursodeoxycholic acid ≥99%

Sigma-Aldrich

U5127

Ursodeoxycholic acid

Desossicolato di sodio ≥97% (titration)

Sigma-Aldrich

D6750

Desossicolato di sodio

Glicochenodesossicolato di sodio ≥97.0% (TLC)

Sigma-Aldrich

50534

Glicochenodesossicolato di sodio

Cholic acid from bovine and/or ovine, ≥98%

Sigma-Aldrich

C1129

Cholic acid

R L Kandell et al.
Nutrition and cancer, 16(3-4), 227-238 (1991-01-01)
Two bile salts, sodium chenodeoxycholate and sodium deoxycholate, induced a DNA repair response in the bacterium Escherichia coli. Similarly, a bile acid and a bile salt, chenodeoxycholic acid and sodium deoxycholate, induced DNA repair (indicated by unscheduled DNA synthesis) in
Sarinya Tawthep et al.
Journal of bioscience and bioengineering, 124(5), 514-522 (2017-07-29)
Understanding the dynamics of secondary bile acid (SBA) formation in the gut by SBA-producing bacteria is important for host health, as SBAs have been shown to affect host pathophysiology and gut microbiota composition. However, our knowledge of SBA producers is
L J Wheeldon et al.
Journal of applied microbiology, 105(6), 2223-2230 (2009-01-06)
To investigate the influence of chemical and physical factors on the rate and extent of germination of Clostridium difficile spores. Germination of C. difficile spores following exposure to chemical and physical germinants was measured by loss of either heat or
V Vanhoorne et al.
Orphanet journal of rare diseases, 14(1), 186-186 (2019-08-03)
Pharmaceutical compounding of orphan active ingredients can offer cost-effective treatment to patients when no other drug product is available for a rare disease or during periods of drug product shortages. Additionally, it allows customized therapy for patients with rare diseases.
Tina Kauss et al.
Journal of pharmaceutical sciences, 108(8), 2805-2813 (2019-03-18)
Current pediatric antibiotic therapies often use oral and parenteral routes of administration. Neither are suitable for treating very sick neonates who cannot take oral medication and may be several hours away from hospital in developing countries. Here, we report on
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