A3785

5-Aminolevulinic acid hydrochloride

≥98%, suitable for ligand binding assays

• Sinonimo/i: δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
• Formula condensata: NH₂CH₂C(O)CH₂CH₂COOH · HCl
• Numero CAS: 5451-09-2
• Peso molecolare: 167.59
• Beilstein: 3690651
• Numero CE: 226-679-5
• Numero MDL: MFCD00012869
• Codice UNSPSC: 12352209
• ID PubChem: 24890811
• NACRES: NA.26

Proprietà

• product name: 5-Aminolevulinic acid hydrochloride, ≥98%
• Livello qualitativo: 300
• Saggio: ≥98%
• Forma fisica: powder
• tecniche: ligand binding assay: suitable
• Punto di fusione: 150 °C
• Temperatura di conservazione: −20°C
• Stringa SMILE: Cl[H].NCC(=O)CCC(O)=O
• InChI: 1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H; ZLHFONARZHCSET-UHFFFAOYSA-N

Descrizione

Applicazioni

5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines. It has also been used in photodynamic therapy for A431 tumor bearing mice.

Azioni biochim/fisiol

5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is useful in cancer treatment. It is a non-protein amino acid. 5-ALA also has applications in the field of agriculture. It is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases, such as Paget′s disease and HPV infection-associated cervical condylomata acuminata.

Intermediate in heme biosynthesis.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable