62962

L-α-Lysophosphatidylcholine

egg yolk, ≥99.0% (TLC)

• Sinonimo/i: 3-sn-Lysophosphatidylcholine, L-α-Lysolecithin
• Numero MDL: MFCD00131444
• Codice UNSPSC: 51321705
• NACRES: NA.25

Proprietà

• Origine biologica: egg yolk
• Descrizione: zwitterionic
• Saggio: ≥99.0% (TLC)
• Forma fisica: powder or solid
• Composizione: 16:0, ~69% (fatty acid); 18:0, ~27% (fatty acid); 18:1, ~3% (fatty acid)
• Solubilità: chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow
• Gruppo funzionale: phospholipid
• Tipo di lipide: phosphoglycerides
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C

Descrizione

Applicazioni

• The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating: L-α-LPC is explored for its unique interaction with ion channels, suggesting its potential as a tool for studying channel mechanics and developing new therapeutic strategies for diseases linked to cellular mechanics (Mukherjee et al., 2014).


• Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter: The use of L-α-LPC in enhancing the delivery of gene therapy vectors via aerosol demonstrates its utility in improving the efficiency of gene therapies, particularly for respiratory diseases (Koehler et al., 2005).

Azioni biochim/fisiol

3-sn-Lysophosphatidylcholine, besides contributing to the positive curvature of membranes , inhibits SNARE complex disassembly in vitro and in rat nerve terminals and exocrine pancrease .

Altre note

Preparation of demembranated frog sperm chromatin

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)