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01148

Sigma-Aldrich

Sodium fluoride

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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About This Item

Formula condensata:
NaF
Numero CAS:
7681-49-4
Peso molecolare:
41.99
Numero CE:
231-667-8
Numero MDL:
MFCD00003524
Codice UNSPSC:
12352302
eCl@ss:
38050104
ID PubChem:
329747226
NACRES:
NA.21

Tensione di vapore

1.4 mmHg ( 0 °C)

Grado

puriss.

Saggio

98.5-100.5% (calc. to the dried substance)

Forma fisica

powder

Qualità

meets analytical specification of Ph. Eur., BP, USP

Impurezze

acidity or alkalinity, complies
 organic volatile impurities, complies (GC)
 residual solvents, complies
≤0.002% heavy metals (as Pb)
≤0.1% free alkali (as NaOH)
≤0.2% free acid (as HF)
≤0.2% sodium hexafluorosilicate (Na2SiF6)

Perdita

≤0.5% loss on drying, 150 °C

Punto di fusione

993 °C (lit.)

Anioni in tracce

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

Cationi in tracce

Fe: ≤50 mg/kg

Compatibilità

complies for appearance of solution

Stringa SMILE

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1
PUZPDOWCWNUUKD-UHFFFAOYSA-M

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Categorie correlate

Descrizione generale

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Applicazioni

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301,H315,H319

Classi di pericolo

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Rischi supp

EUH032

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Hye-Jin Lee et al.
The Kaohsiung journal of medical sciences, 31(6), 303-308 (2015-06-05)
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and
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