92107

O-Acetyl-L-carnitine hydrochloride

analytical standard

• Sinonimo/i: (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride, ALC, ALCAR, R-(−)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
• Formula empirica (notazione di Hill): C₉H₁₇NO₄ · HCl
• Numero CAS: 5080-50-2
• Peso molecolare: 239.70
• Beilstein: 4340103
• Numero MDL: MFCD00082230
• Codice UNSPSC: 41116107
• NACRES: NB.21

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Saggio: ≥96.0% (HPLC); 96.0-104.0% (AT)
• Forma fisica: powder or crystals
• Attività ottica: [α]/D -27.0±2.0°, c = 1 in H₂O
• Durata: limited shelf life, expiry date on the label
• Colore: white to off-white
• applicazioni: clinical testing
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C[N+](C)(C)C[C@H](OC(C)=O)CC(O)=O.[Cl-]
• InChI: 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1; JATPLOXBFFRHDN-DDWIOCJRSA-N

Descrizione

Descrizione generale

Acetyl carnitine is one of the major acylcarnitines produced during the transport of long-chain fatty acids in the body.

Applicazioni

O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.

Azioni biochim/fisiol

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Prodotti consigliati

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Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable