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03880590

Luteolin

primary reference standard

Sinonimo/i:

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Formula empirica (notazione di Hill):
C15H10O6
Numero CAS:
491-70-3
Peso molecolare:
286.24
Beilstein:
292084
Numero CE:
207-741-0
Numero MDL:
MFCD00017309
Codice UNSPSC:
85151701
ID PubChem:
329747828
NACRES:
NA.24

Grado

primary reference standard

Durata

limited shelf life, expiry date on the label

Produttore/marchio commerciale

HWI

Punto di fusione

~330 °C (lit.)

applicazioni

food and beverages

Stringa SMILE

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
IQPNAANSBPBGFQ-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Applicazioni

Reference Standard in the analysis of herbal medicinal products

Altre note

This compound is commonly found in plants of the genus: achillea

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
HWI03169
HWI02485-1
HWI02485
HWI02293
HWI02063-1

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Luteolin 7-O-β-D-glucoside ≥98.0% (HPLC)

Sigma-Aldrich

74284

Luteolin 7-O-β-D-glucoside

Apigenin ≥97% (TLC), from citrus

Sigma-Aldrich

SMB00702

Apigenin

Apigenin 7-glucoside primary reference standard

00720585

Apigenin 7-glucoside

Kaempferol United States Pharmacopeia (USP) Reference Standard

USP

1354900

Kaempferol

Diosmetin

Sigma-Aldrich

D7321

Diosmetin

Kaempferol analytical standard

Supelco

96353

Kaempferol

Acido citrico anhydrous for synthesis

Sigma-Aldrich

8.18707

Acido citrico

Lien Verschooten et al.
PloS one, 7(10), e48264-e48264 (2012-10-31)
Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma
Poyil Pratheeshkumar et al.
PloS one, 7(12), e52279-e52279 (2013-01-10)
Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid found in fruits and vegetables. We studied the antiangiogenic activity of luteolin using in vitro
Theoharis C Theoharides et al.
Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Benguo Liu et al.
Food chemistry, 141(2), 900-906 (2013-06-26)
The formation of supramolecular inclusion complexes between luteolin and five cyclodextrins namely β-cyclodextrin (β-CD), methyl-β-cyclodextrin (M-β-CD), hydroxyethyl-β-cyclodextrin (HE-β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD) and glucosyl-β-cyclodextrin (G-β-CD) was investigated. Results from phase-solubility studies showed that luteolin formed 1:1 stoichiometric inclusion complexes with these cyclodextrins
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