00410

Ethyl acetoacetate

puriss. p.a., ≥99.0% (GC)

• Sinonimo/i: Acetoacetic ester
• Formula condensata: CH₃COCH₂COOC₂H₅
• Numero CAS: 141-97-9
• Peso molecolare: 130.14
• Beilstein: 385838
• Numero CE: 205-516-1
• Numero MDL: MFCD00009199
• Codice UNSPSC: 12352100
• eCl@ss: 39022303
• ID PubChem: 329747065
• NACRES: NA.22

Proprietà

• Densità del vapore: 4.48 (vs air)
• Livello qualitativo: 200
• Tensione di vapore: 1 mmHg ( 28.5 °C)
• Grado: puriss. p.a.
• Saggio: ≥99.0% (GC)
• Temp. autoaccensione: 580 °F
• Limite di esplosione: 9.5 %
• Impurezze: ≤0.5% water
• Indice di rifrazione: n20/D 1.419
• P. eboll.: 181 °C (lit.)
• Punto di fusione: −43 °C (lit.)
• Solubilità: water: soluble 130 g/L at 20 °C
• Densità: 1.029 g/mL at 20 °C (lit.)
• Cationi in tracce: Al: ≤0.5 mg/kg; Ba: ≤0.1 mg/kg; Bi: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; K: ≤0.5 mg/kg; Li: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Mo: ≤0.1 mg/kg; Na: ≤0.5 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sr: ≤0.1 mg/kg; Zn: ≤0.5 mg/kg
• Gruppo funzionale: ester; ketone
• Stringa SMILE: CCOC(=O)CC(C)=O
• InChI: 1S/C6H10O3/c1-3-9-6(8)4-5(2)7/h3-4H2,1-2H3; XYIBRDXRRQCHLP-UHFFFAOYSA-N

Descrizione

Applicazioni

Ethyl acetoacetate can be used as a reactant in the synthesis of:

• Knoevenagel condensation products by reacting with α-alkylideneacetoacetate and aliphatic, aromatic, heteroaromatic aldehydes.
• Michael adducts, via Michael addition reaction with chalcones and azachalcones in the presence of a base catalyst.
• Substituted nicotinic acid derivatives by treating with α, β-unsaturated oximes via Michael addition followed by ring closure reaction.

It can be also utilized as a reactant in the transesterification and asymmetric hydrogenation reactions to produce valuable products.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 164.3 °F - closed cup
• Punto d’infiammabilità (°C): 73.5 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type ABEK (EN14387) respirator filter