MAB3318
Anti-TIMP-3 Antibody, a.a. 170-188, clone 136-13H4
clone 136-13H4, Chemicon®, from mouse
Sinonimo/i:
Tissue Inhibitor of Metalloproteinase-3
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
136-13H4, monoclonal
Reattività contro le specie
rabbit, human
Produttore/marchio commerciale
Chemicon®
tecniche
immunohistochemistry: suitable (paraffin)
western blot: suitable
Isotipo
IgG1κ
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... TIMP3(7078)
Specificità
Specifically reacts with human TIMP-3. This is a purified mouse monoclonal antibody to an oligopeptide of SWYRGWAPPDKSIINATDP (residue 170-188) on human tissue inhibitor of metalloproteinases-3 (human TIMP-3).
MAB3318 cross-reacts with rabbit TIMP-3, but does not react with human TIMP-1 and human TIMP-2.
MAB3318 cross-reacts with rabbit TIMP-3, but does not react with human TIMP-1 and human TIMP-2.
Immunogeno
Epitope: a.a. 170-188
Oligopeptide of SWYRGWAPPDKSIINATDP (residue 170-188) on human tissue inhibitor of metalloproteinases-3.
Applicazioni
Anti-TIMP-3 Antibody, a.a. 170-188, clone 136-13H4 is an antibody against TIMP-3 for use in IH(P) & WB.
Immunoblotting: 2 ug/mL
Immunohistochemistry (Paraffin):10ug/mL
Immunohistochemistry (Frozen): 2 ug/mL
Immunohistochemistry (Paraffin):10ug/mL
Immunohistochemistry (Frozen): 2 ug/mL
Research Category
Cell Structure
Cell Structure
Research Sub Category
MMPs & TIMPs
MMPs & TIMPs
Descrizione del bersaglio
26 kDa
Stato fisico
Format: Purified
Liquid in 0.1 M sodium phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.
Protein A purified
Stoccaggio e stabilità
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Risultati analitici
Control
Breast carcinoma tissue
Breast carcinoma tissue
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Manufactured by Daiichi Fine Chemical Co., Ltd
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Interleukin-10 regulates TNF-alpha-converting enzyme (TACE/ADAM-17) involving a TIMP-3 dependent and independent mechanism.
Fionula M Brennan,Patricia Green,Parisa Amjadi,Heidi J Robertshaw et al.
European Journal of Immunology null
Catabolic properties of microdissected human endosteal bone lining cells.
C Dierkes,M Kreisel,A Schulz,J Steinmeyer,J-C Wolff,L Fink
Calcified Tissue International null
S S Apte et al.
Genomics, 19(1), 86-90 (1994-01-01)
The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. We have isolated overlapping cDNAs encoding a novel human TIMP, TIMP-3. The cDNAs contain
C G Wilde et al.
DNA and cell biology, 13(7), 711-718 (1994-07-01)
The tissue inhibitors of metalloproteinases (TIMPs) comprise a family of proteins, of which two members have so far been described in humans. We have cloned and sequenced a third human TIMP (hTIMP-3) from phorbol ester-differentiated THP-1 cells stimulated with bacterial
Lluis Catasus et al.
Histopathology, 62(4), 632-641 (2013-02-06)
Expression of tissue inhibitor of metalloproteinases-3 (TIMP-3) has been found to be decreased in several types of cancer by promoter gene hypermethylation. However, little is known regarding the silencing effect of TIMP3 promoter hypermethylation on gene and protein expression in
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