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Merck
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Key Documents

07-363

Sigma-Aldrich

Anti-AMPK α2 Antibody

Upstate®, from rabbit

Sinonimo/i:

AMP-Activated Protein Kinase, AMPK

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human, rat

Produttore/marchio commerciale

Upstate®

tecniche

western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_006252

N° accesso UniProt

P54646

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... PRKAA2(5563)

Specificità

Recognizes AMP-Activated Protein Kinase alpha2 (AMPKα2).

Immunogeno

peptide corresponding to amino acids 353-367 (C-DDSAMHIPPGLKPHP) of human AMP-Activated Protein Kinase alpha2 (AMPKalpha2) catalytic subunit

Applicazioni

Detect AMPK α2 using this Anti-AMPK α2 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualità

routinely evaluated by immunoblot in a rat liver preparation

Descrizione del bersaglio

~63 kDa

Stato fisico

Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Protein A purified

Stoccaggio e stabilità

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Risultati analitici

Control
Rat liver preparation

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein.
Rowlands, DS; Thomson, JS; Timmons, BW; Raymond, F; Fuerholz, A; Mansourian, R; Zwahlen et al.
Physiological Genomics null
Miki Tadaishi et al.
American journal of physiology. Endocrinology and metabolism, 300(2), E341-E349 (2010-11-26)
There are three isoforms of peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) mRNA, which promotes mitochondrial biogenesis in skeletal muscles. Compared with PGC-1α-a mRNA, PGC-1α-b or PGC-1α-c mRNA is transcribed by a different exon 1 of the PGC-1α gene. In this
Data in support of 5'AMP-activated protein kinase alpha regulates stress granule biogenesis.
Mahboubi, H; Barise, R; Stochaj, U
Data in Brief null
B J Michell et al.
The Journal of biological chemistry, 271(45), 28445-28450 (1996-11-08)
The 5'-AMP-activated protein kinase (AMPK) mediates several cellular responses to metabolic stress. Rat liver contains at least two isoforms of this enzyme, either alpha1 or alpha2 catalytic subunits together with beta and gamma noncatalytic subunits in a trimeric complex. The
TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.
An, D; Toyoda, T; Taylor, EB; Yu, H; Fujii, N; Hirshman, MF; Goodyear, LJ
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