A-003

6-Acetylmorphine, 100 μg/mL solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Sinonimo/i: 6-Acetylmorphine solution
• Formula empirica (notazione di Hill): C₁₉H₂₁NO₄
• Numero CAS: 2784-73-8
• Peso molecolare: 327.37
• Numero CE: 200-835-2
• Numero MDL: MFCD00467140
• Codice UNSPSC: 41116107
• ID PubChem: 329770565
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Livello qualitativo: 300
• Stato: liquid
• Caratteristiche: SNAP-N-SPIKE^®. SNAP-N-SHOOT^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• Concentrazione: 100 μg/mL in acetonitrile
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: forensics and toxicology
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35
• InChI: 1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1; JJGYGPZNTOPXGV-SSTWWWIQSA-N

Descrizione

Descrizione generale

6-Acetylmorphine, also known as 6-monoacetylmorphine or 6-MAM, is an active metabolite of heroin and biomarker for heroin usage. This Certified Spiking Solution^® is suitable for use as a starting material in calibrators and controls for GC/MS or LC/MS methods in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.

Applicazioni

• Drug use monitoring: The utility of 6-acetylmorphine as a specific biomarker in workplace drug testing for identifying illicit heroin use among morphine-positive urine specimens was highlighted, affirming its importance in forensic and clinical toxicology (Vikingsson et al., 2024).


• Physiological monitoring technology: The detection of 6-acetylmorphine in sweat at the molecular level demonstrates the potential of the wearable SERS sensor in monitoring drug use (Liu et al., 2024).


• Drug effect attenuation research: A bivalent conjugate vaccine inducing dual immunogenic responses was studied to attenuate the effects of heroin and fentanyl in mice, utilizing 6-acetylmorphine as a component, demonstrating its potential in therapeutic developments (Barrientos et al., 2021).


• Behavioral toxicology: The determination of drugs of abuse in hair samples using LC-MS/MS, which included 6-acetylmorphine, provided vital data for investigations related to suicide attempts, highlighting its utility in clinical and forensic toxicology (Cardoso et al., 2022).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H302 + H312 + H332,H319
• Consigli di prudenza: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 35.6 °F - closed cup
• Punto d’infiammabilità (°C): 2 °C - closed cup