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M-005

Supelco

Morphine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C17H19NO3
Numero CAS:
57-27-2
Peso molecolare:
285.34
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material

Livello qualitativo

300

Stato

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Concentrazione

1.0 mg/mL in methanol

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

forensics and toxicology

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35

InChI

1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
BQJCRHHNABKAKU-KBQPJGBKSA-N

Informazioni sul gene

human ... OPRM1(4988)

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Categorie correlate

Descrizione generale

This certified analytical reference standard is suitable for a variety of GC/MS or LC/MS applications from pain prescription monitoring, clinical toxicology, and urine drug testing to pharmaceutical research and forensic analysis.

Morphine is a natural phenolic alkaloid, commonly used as an analgesic and anti-inflammatory properties. Sold under trade names including MS Contin®, Kadian®, Oramorph®, and Roxanol, morphine is also a commonly abused recreational drug due to its widespread availability and a high potential for addiction.

Applicazioni

The certified reference solution (CRM) in solution can also be used as follows:
  • Development of a hydrogel-modified carbon paste electrode (HCPE) for the electrochemical determination of morphine in very low volume solutions using differential pulse voltammetry
  • Combination of magnetic molecularly imprinted solid phase extraction (MMISPE) with high-performance liquid chromatography (HPLC) to analyze urine samples for quantifying morphine
  • Electrochemical detection and measurement of morphine and 3,4-methylenedioxymethamphetamine (MDMA) in human urine and serum samples using carbon nanohorns modified with Pt nanoparticles (CNHs@PtNPs) based sensor
  • Simultaneous determination of morphine and naltrexone in bulk and their combined solid dosage formulations using a stability-indicating high-performance liquid chromatographic method combined with a photodiode array detector
  • Colorimetric estimation of morphine and ibuprofen in human serum and urine samples as per the difference in the aggregation of citrate-capped gold nanoparticles (AuNPs) analyzed by infra-red (IR) spectroscopy and transmission electron microscopy (TEM)

Caratteristiche e vantaggi

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Kadian is a registered trademark of Actavis Elizabeth LLC
MS Contin is a registered trademark of Purdue Frederick Company
Oramorph is a registered trademark of AAIPharma, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Morphine solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes,Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

Elenchi normativi

Forniamo informazioni su eventuali restrizioni prevalentemente per i prodotti chimici. Per altre tipologie di prodotto siamo in grado di fornire soltanto informazioni limitate. Nessuna segnalazione significa che nessuno dei componenti è citato in un elenco. È dovere dell’utilizzatore assicurarsi che il prodotto venga impiegato in maniera sicura e a norme di legge.

EU REACH Annex XVII (Restriction List)

CAS No.

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

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Mean versus median in tables and figures.
Tim Thomas Joseph et al.
Anesthesia and analgesia, 116(6), 1390-1391 (2013-05-28)
In response.
Alain Gorgeat
Anesthesia and analgesia, 116(6), 1391-1391 (2013-07-12)
Importance of reducing pain during routine procedures.
Michael C Petty
Journal of the American Veterinary Medical Association, 242(8), 1048-1048 (2013-05-15)
Thitima Chinachoti et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(5), 589-594 (2013-06-12)
Presently, in Siriraj Hospital, intrathecal morphine is routinely used in spinal anesthesia for postoperative pain control in more than 600 cases per month with doses lower than 0.3 mg. However, the incidence of side effects is high. This retrospective data
A Bilir
Clinical and experimental obstetrics & gynecology, 40(1), 118-121 (2013-06-04)
Pain management has a particular importance after Cesarean section. This study was undertaken in order to document the efficacy and side-effects of epidural morphine instead of patient-controlled analgesia technique used for the control of post-cesarean pain during postoperative 24-48 hours.
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Articoli

Benefits of Ascentis Express Phenyl-Hexyl over Biphenyl for the Separation of Pain Management Opiates

Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.

Protocolli

LC/MS (TOF) Analysis of Drugs and Their Glucuronide Metabolites in Urine on Titan™ C18 after Solid Phase Extraction (SPE) using Supel™-Select SCX, β-Glucuronidase Enzyme Digestion

-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

Using UHPLC/MS (TOF) for Detection of Drugs and Metabolites in Urine Following Optimized Enzymatic Hydrolysis Conditions

To optimize hydrolysis using β-glucuronidase, factors such as incubation time, temperature, hydrolysis pH, enzyme source, and enzyme concentration must be evaluated for each glucuronide metabolite to be analyzed.

Global Trade Item Number

SKUGTIN
M-005-1ML4061837819438

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