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W296902

Sigma-Aldrich

Pyruvaldehyde solution

40 wt. % in H2O

Sinonimo/i:

Methylglyoxal solution, Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde

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About This Item

Formula condensata:
CH3COCHO
Numero CAS:
78-98-8
Peso molecolare:
72.06
Numero FEMA:
2969
Beilstein:
906750
N° CoE:
105
Numero MDL:
MFCD00006960
Codice UNSPSC:
12164502
ID PubChem:
24901425
Numero Flavis:
7.001
NACRES:
NA.21

Origine biologica

synthetic

Grado

Halal

Concentrazione

40 wt. % in H2O

Indice di rifrazione

n20/D 1.41

Densità

1.178 g/mL at 25 °C

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Organolettico

caramel

Temperatura di conservazione

2-8°C

Stringa SMILE

[H]C(=O)C(C)=O

InChI

1S/C3H4O2/c1-3(5)2-4/h2H,1H3
AIJULSRZWUXGPQ-UHFFFAOYSA-N

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Descrizione generale

Pyruvaldehyde solution may be used along with ammonium salts to prepare aqueous solutions that mimic atmospheric aerosol compositions to study the formation of absorbing secondary organic materials.

Esclusione di responsabilità

For R&D or non-EU Food use. Not for retail sale.

Avvertenze

Danger

Indicazioni di pericolo

H290,H317,H318,H341

Classi di pericolo

Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
SHBP2833
STBK2288
STBJ3575
STBJ2962
STBJ1443

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Sigma-Aldrich

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Sigma-Aldrich

8.20610

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DL-Glyceraldehyde ≥90% (GC)

Sigma-Aldrich

G5001

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DL-Glyceraldehyde 3-phosphate solution 45-55 mg/mL in H2O

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Dihydroxyacetone for synthesis

Sigma-Aldrich

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Sigma-Aldrich

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anti-Pyruvic aldehyde 1-oxime

Secondary organic material formed by methylglyoxal in aqueous aerosol mimics.
Sareen N, et al.
Atmospheric Chemistry and Physics, 10(3) (2010)
T W Lo et al.
Biochemical pharmacology, 48(10), 1865-1870 (1994-11-16)
Increased formation of methylglyoxal in clinical diabetes mellitus and metabolism by the glyoxalase system has been linked to the development of clinical complications of diabetes: retinopathy, neuropathy and nephropathy. Aminoguanidine has been proposed as a prophylactic agent for preventive therapy
Georg T Wondrak et al.
Biochemical pharmacology, 63(3), 361-373 (2002-02-21)
Tissue deterioration and aging have long been associated with the accumulation of chemically induced protein and DNA damage. Reactive oxygen species (ROS) and reactive carbonyl species (RCS), especially alpha-dicarbonyl compounds, are key mediators of damage caused by oxidative stress, glycation
Wei-Hsuan Hsu et al.
Toxicology and applied pharmacology, 272(3), 842-851 (2013-08-21)
Methylglyoxal (MG) is a toxic-glucose metabolite and a major precursor of advanced glycation endproducts (AGEs). MG has been reported to result in inflammation by activating receptor for AGEs (RAGE). We recently found that Monascus-fermented metabolite monascin acts as a novel
Paul J Beisswenger et al.
Diabetes, 54(11), 3274-3281 (2005-10-27)
Dicarbonyl and oxidative stress may play important roles in the development of diabetes complications, and their response to hyperglycemia could determine individual susceptibility to diabetic nephropathy. This study examines the relationship of methylglyoxal, 3-deoxyglucosone (3DG), and oxidative stress levels to
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