919381

CCW16

≥95%

• Sinonimo/i: N-Benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide, E3 ubiquitin ligase ligand, Ligand for PROTAC^® research, RNF4-targeting ligand
• Formula empirica (notazione di Hill): C₂₂H₂₀ClNO₃
• Numero CAS: 2361138-33-0
• Peso molecolare: 381.85

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95%
• Forma fisica: powder
• Impiego in reazioni chimiche: reagent type: ligand
• Gruppo funzionale: amine
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: COC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1

Descrizione

Applicazioni

CCW16 is targeting ligand for the E3 ubiquitin ligase RNF4 (RING finger protein 4) and can be used in targeted protein degradation (TPD) research or in the synthesis of protein degraders. Learn more about proteolysis-targeting chimeras (PROTAC degraders) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation.

Altre note

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Targeted Protein Degradation by Small Molecules

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Note legali

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Informazioni sulla sicurezza

• Pittogrammi: GHS09
• Avvertenze: Warning
• Indicazioni di pericolo: H410
• Consigli di prudenza: P273 - P391 - P501
• Classi di pericolo: Aquatic Acute 1 - Aquatic Chronic 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable