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850993

Sigma-Aldrich

2-Aminoisobutyic acid

98%, for peptide synthesis

Sinonimo/i:

α-Aminoisobutyric acid, 2-Methylalanine, Aib

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About This Item

Formula condensata:
(CH3)2C(NH2)COOH
Numero CAS:
Peso molecolare:
103.12
Beilstein:
506496
Numero CE:
Numero MDL:
Codice UNSPSC:
12352106
ID PubChem:
NACRES:
NA.22

Nome del prodotto

2-Aminoisobutyic acid, 98%

Livello qualitativo

Saggio

98%

Stato

solid

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

≥300 °C

applicazioni

peptide synthesis

Stringa SMILE

CC(C)(N)C(O)=O

InChI

1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
FUOOLUPWFVMBKG-UHFFFAOYSA-N

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Descrizione generale

2-Aminoisobutyric acid also known as α-aminobutyric acid, is an amino acid used in solution-phase peptide synthesis. It is a desirable building block for peptides because of its strong tendency to cause the peptide to form a helical shape.

Applicazioni

2-Aminoisobutyric acid can be used to synthesize self-assembled polypeptide nanoparticles. Incorporation of this compound into the peptide chain can prevent undesired reactions since it is di-α-substituted, and inert to C−H abstraction.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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We use mixed classical/quantum simulations to study the time dependence of an excitation of a C=O vibration on a 3-10 helix of α-aminoisobutyric acid, a system which represents a test case for the formation of self-trapped vibrational excitation states on

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