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30170

Sigma-Aldrich

L-Cysteic acid monohydrate

≥99.0% (T), suitable for LC/MS

Sinonimo/i:

(R)-2-Amino-3-sulfopropionic acid

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About This Item

Formula condensata:
HO3SCH2CH(NH2)CO2H·H2O
Numero CAS:
23537-25-9
Peso molecolare:
187.17
Beilstein:
3714036
Numero MDL:
MFCD00149544
Codice UNSPSC:
12352209
ID PubChem:
24858207
NACRES:
NA.26

Nome del prodotto

L-Cysteic acid monohydrate, ≥99.0% (T)

Livello qualitativo

200

Saggio

≥99.0% (T)

Stato

powder or crystals

Attività ottica

[α]20/D +7.5±0.5°, c = 5% in H2O

tecniche

LC/MS: suitable

Colore

white to faint yellow

Punto di fusione

267 °C (dec.) (lit.)

Solubilità

H2O: soluble

applicazioni

peptide synthesis

Stringa SMILE

[H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O

InChI

1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1
PCPIXZZGBZWHJO-DKWTVANSSA-N

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Applicazioni

Internal standard for amino acid analysis.

Azioni biochim/fisiol

L-Cysteic acid is a sulfur containing aspartate analogue that may be used as a competitive inhibitor of the bacterial aspartate:alanine antiporter (AspT) exchange of aspartate and in other aspartate biological systems. L-Cysteic acid is used in monomeric surfactant development.
L-cysteic acid is an oxidation product of L-cysteine. L-Cysteic acid, an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain, such as those that bind to cysteine sulfinic acid receptors. L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors (mGluRs).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCF8492
BCCF8140
BCCF7794
BCCF7396
BCCD0794

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B Meldrum
Epilepsia, 25 Suppl 2, S140-S149 (1984-01-01)
Amino acids provide the most universal and important inhibitory (gamma-aminobutyric acid (GABA), glycine) and excitatory (glutamate, aspartate, cysteic acid, cysteine sulphinic acid) neurotransmitters in the brain. An anticonvulsant action may be produced (1) by enhancing inhibitory (GABAergic) processes, and (2)
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
Qi Shi et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 131-142 (2003-03-22)
Moderate hyperhomocysteinemia is associated with several diseases, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, and spina bifida. However, the mechanisms for their pathogenesis are unknown but could involve the interaction of homocysteine or its metabolites with molecular targets such
A E Kingston et al.
Neuropharmacology, 37(3), 277-287 (1998-07-29)
Comparison of the pharmacological effects of a range of sulphur-containing amino acids on human mGluR1alpha and mGluR5a has been undertaken. cDNAs of each mGluR were transfected into a Syrian hamster tumour cell line AV12-664 that was previously transfected with the
Naoko Arashida et al.
Analytica chimica acta, 954, 77-87 (2017-01-14)
Amino acids and their related metabolites play important roles in various physiological processes and have consequently become biomarkers for diseases. However, accurate quantification methods have only been established for major compounds, such as amino acids and a limited number of

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