512834

3-(Hydroxymethyl)phenylboronic acid

≥95%

• Sinonimo/i: 3-Hydroxymethylbenzeneboronic acid
• Formula condensata: HOCH₂C₆H₄B(OH)₂
• Numero CAS: 87199-15-3
• Peso molecolare: 151.96
• Numero MDL: MFCD01317846
• Codice UNSPSC: 12352103
• ID PubChem: 24873658
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95%
• Punto di fusione: 95-99 °C (lit.)
• Gruppo funzionale: hydroxyl
• Stringa SMILE: OCc1cccc(c1)B(O)O
• InChI: 1S/C7H9BO3/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4,9-11H,5H2; HGTDLKXUWVKLQX-UHFFFAOYSA-N

Descrizione

Applicazioni

Reactant involved in:

• Copper-mediated trifluoromethylation
• Copper-catalyzed transformations from arylboronic acids in water
• Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylate

Reactant involved in the synthesis of biologically active molecules including:

• Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions
• HIV protease inhibitors with antiviral activity against drug-resistant viruses
• Pyrrole derivatives for use as PDE4B inhibitors

Altre note

Contains varying amounts of anhydride

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)